Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1016/j.theriogenology.2016.11.033 |
Maternal recognition of pregnancy and implantation are not associated with an interferon response of the endometrium to the presence of the conceptus in dromedary camel | |
Abdoon, Ahmed Sabry Salah1; Giraud-Delville, Corrine2; Kandil, Omaima Mohamed1; Kerboeuf-Giraud, Annelye2; Eozenou, Caroline3; Carvalho, Anais Vitorino2; Julian, Skidmore4; Sandra, Olivier2 | |
通讯作者 | Abdoon, Ahmed Sabry Salah |
来源期刊 | THERIOGENOLOGY
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ISSN | 0093-691X |
EISSN | 1879-3231 |
出版年 | 2017 |
卷号 | 90页码:301-308 |
英文摘要 | Maternal recognition of pregnancy (MRP) and implantation involve appropriate interactions between the elongating conceptus and the receptive endometrium that will condition development of the feto-placental unit to term. Molecular mechanisms that take place at the conceptus-endometrium interface during early pregnancy have been extensively investigated in domestic ungulates but they are still poorly understood in camelids including the dromedary camel (Camelus dromedarius), a domestic species with important economic and social roles in arid and semi-arid areas. In order to better understand how MRP and implantation take place in the left horn of this species, we investigated expression levels of genes encoding steroid hormones (PGR, ESR1), transcription factors (STAT1, FOXL2), interferon stimulated genes (MXI, MX2, OAS1, RSAD2) including SOCS genes (SOCS1, SOCS2, SOCS3 and CISH), previously identified as conceptus regulated genes in the endometrium of other domestic animals. Using endometrial tissue collected from left and right uterine horns of dromedary camel females that were non pregnant or early pregnant, gene expression of these genes was detected and our results provided first insights on their regulation, showing that (i) conceptus implantation is not associated with an IFN response in the pregnant uterine horn (ii) when regulation of classical interferon-stimulated genes (ISG) occurs, it takes place during the formation of the feto-placental unit, and (iii) gene expression can differ between the left and right uterine horns during implantation and early placentation phase. Additional experiments will be required in dromedary camels to understand the unusual regulation of ISG during implantation as well as to determine the molecular processes that drive the systematic implantation of the elongating conceptus in the left uterine horn. (C) 2017 Elsevier Inc. All rights reserved. |
英文关键词 | Dromedary camel Gene expression Maternal recognition of pregnancy Left horn pregnancy |
类型 | Article |
语种 | 英语 |
国家 | Egypt ; France ; U Arab Emirates |
收录类别 | SCI-E |
WOS记录号 | WOS:000394195400041 |
WOS关键词 | CORPUS-LUTEUM ; ESTROUS-CYCLE ; SOCS GENES ; PROGESTERONE ; EXPRESSION ; ESTABLISHMENT ; MECHANISMS ; RECEPTORS ; RUMINANTS ; EMBRYO |
WOS类目 | Reproductive Biology ; Veterinary Sciences |
WOS研究方向 | Reproductive Biology ; Veterinary Sciences |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/202692 |
作者单位 | 1.Natl Res Ctr, Vet Res Div, Dept Anim Reprod & Artificial Inseminat, Cairo 12622, Egypt; 2.INRA, UMR1198, Biol Dev & Reprod, F-78352 Jouy En Josas, France; 3.Univ Paris Saclay, ENVA, INRA, UMR BDR, F-78350 Jouy En Josas, France; 4.Camel Reprod Ctr, Dubai, U Arab Emirates |
推荐引用方式 GB/T 7714 | Abdoon, Ahmed Sabry Salah,Giraud-Delville, Corrine,Kandil, Omaima Mohamed,et al. Maternal recognition of pregnancy and implantation are not associated with an interferon response of the endometrium to the presence of the conceptus in dromedary camel[J],2017,90:301-308. |
APA | Abdoon, Ahmed Sabry Salah.,Giraud-Delville, Corrine.,Kandil, Omaima Mohamed.,Kerboeuf-Giraud, Annelye.,Eozenou, Caroline.,...&Sandra, Olivier.(2017).Maternal recognition of pregnancy and implantation are not associated with an interferon response of the endometrium to the presence of the conceptus in dromedary camel.THERIOGENOLOGY,90,301-308. |
MLA | Abdoon, Ahmed Sabry Salah,et al."Maternal recognition of pregnancy and implantation are not associated with an interferon response of the endometrium to the presence of the conceptus in dromedary camel".THERIOGENOLOGY 90(2017):301-308. |
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