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DOI | 10.12968/jowc.2017.26.Sup1.S12 |
Cost-effectiveness of using adjunctive porcine small intestine submucosa tri-layer matrix compared with standard care in managing diabetic foot ulcers in the US | |
Guest, J. F.1,2,4,5; Weidlich, D.3; Singh, H.3; La Fontaine, J.6; Garrett, A.7; Abularrage, C. J.8,9; Waycaster, C. R.10 | |
通讯作者 | Guest, J. F. |
来源期刊 | JOURNAL OF WOUND CARE
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ISSN | 0969-0700 |
EISSN | 2062-2916 |
出版年 | 2017 |
卷号 | 26期号:1页码:S12-S24 |
英文摘要 | Objective: To estimate the cost-effectiveness of using tri-layer porcine small intestine submucosa (SIS; Oasis Ultra) as an adjunct to standard care compared with standard care alone in managing diabetic foot ulcers (DFUs) in the US, from the perspective of Medicare. Method: A Markov model was constructed to simulate the management of diabetic neuropathic lower extremity ulcers over a period of one year in the US. The model was used to estimate the cost-effectiveness of initially using adjunctive SIS compared with standard care alone to treat a DFU in the US at 2016 prices. Results: At 12 months after the start of treatment, the use of adjunctive SIS instead of standard care alone is expected to lead to a 42 % increase in the number of ulcer-free months, 32 % increase in the probability of healing, a 3 % decrease in the probability of developing complicated ulcers and a 1 % decrease in the probability of undergoing an amputation. Health-care resource use is expected to be reduced by 11-14 % among patients who are initially managed with adjunctive SIS compared with those initially managed with standard care alone, with the exception of debridement, which is expected to be reduced by 35 %. Hence, the total health-care cost of starting treatment with adjunctive SIS instead of standard care alone was estimated to reduce payer costs by 1% (i. e. $ 105 per patient) over 12 months following the start of treatment. Conclusion: Within the study’s limitations, the use of adjunctive SIS instead of standard care alone improves outcome for less cost and thereby affords a cost-effective use of Medicare-funded resources in the management of neuropathic foot ulcers among adult patients with type 1 or 2 diabetes mellitus in the US. |
英文关键词 | cost-effectiveness diabetic foot ulcer Oasis Ultra porcine small intestine submucosa tri-layer matrix United States |
类型 | Article |
语种 | 英语 |
国家 | England ; USA |
收录类别 | SCI-E |
WOS记录号 | WOS:000392426600003 |
WOS关键词 | MANAGEMENT |
WOS类目 | Dermatology |
WOS研究方向 | Dermatology |
来源机构 | University of London |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/200902 |
作者单位 | 1.Catalyst Hlth Econ Consultants, Catalyst, Northwood, Middx, England; 2.Catalyst Hlth Econ Consultants, Hlth Econ, Northwood, Middx, England; 3.Catalyst Hlth Econ Consultants, Northwood, Middx, England; 4.Kings Coll London, Fac Life Sci & Med, Catalyst, London, England; 5.Kings Coll London, Fac Life Sci & Med, Hlth Econ, London, England; 6.Univ Texas Southwestern Med Ctr Dallas, Plast Surg, Dallas, TX 75390 USA; 7.Ben Hogan Bone & Joint Clin, Ft Worth, TX USA; 8.Johns Hopkins Univ Hosp, Diabet Foot & Wound Clin, Surg, Baltimore, MD 21287 USA; 9.Johns Hopkins Univ Hosp, Diabet Foot & Wound Clin, Multidisciplinary Diabet Foot & Wound Clin, Baltimore, MD 21287 USA; 10.Smith & Nephew Biotherapeut, Hlth Econ, Ft Worth, TX USA |
推荐引用方式 GB/T 7714 | Guest, J. F.,Weidlich, D.,Singh, H.,et al. Cost-effectiveness of using adjunctive porcine small intestine submucosa tri-layer matrix compared with standard care in managing diabetic foot ulcers in the US[J]. University of London,2017,26(1):S12-S24. |
APA | Guest, J. F..,Weidlich, D..,Singh, H..,La Fontaine, J..,Garrett, A..,...&Waycaster, C. R..(2017).Cost-effectiveness of using adjunctive porcine small intestine submucosa tri-layer matrix compared with standard care in managing diabetic foot ulcers in the US.JOURNAL OF WOUND CARE,26(1),S12-S24. |
MLA | Guest, J. F.,et al."Cost-effectiveness of using adjunctive porcine small intestine submucosa tri-layer matrix compared with standard care in managing diabetic foot ulcers in the US".JOURNAL OF WOUND CARE 26.1(2017):S12-S24. |
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