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Stenocereus eruca is a columnar horizontally grown cactus that can "move" on the ground relatively fast. It is considered an endangered species and endemic to a very small extension of land in Baja California Sur, Mexico. Seedling recruitment seems to be a big problem for its propagation; however, it can propagate asexually. There is strong evidence that seed pretreatment with organic solvents affect seed germination ability. Thus, the objective of this study was to determine the effect of treating chirinola seeds, collected from Puerto San Carlos area, with different solvents in terms of rate and total germination. The experiment was arranged in a completely randomized design using two different solvents (acetone and dichloromethane) with four replicates of 25 seeds each one. Pre-treatment of chirinola seeds with acetone increased total germination almost double (62%) as compared to the control (32%). On the other hand, pre-treatment of the seeds with dichloromethane reduced total germination to 0%. The use of this two solvent for pre-treatment of the seeds had very different effect of germination making acetone a suitable solvent in order to increase total germination of chirinola seeds.