干旱区生态环境知识资源中心(Arid): Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula

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DOI	10.1021/acs.jnatprod.7b00106
	Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula
	Hassan, Ahmed R.1,5; El-Kousy, Salah M.2; El-Toumy, Sayed A.3; Frydenyang, Karla 1; Truong Thanh Tung 1; Olsen, Jesper 4; Nielsen, John 1; Christensen, Soren Bragger 1
通讯作者	Nielsen, John ; Christensen, Soren Bragger
来源期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
EISSN	1520-6025
出版年	2017
卷号	80 期号:10 页码:2830-2834
英文摘要	A phytochemical investigation of Seidlitzia rosmarinus collected along the shoreline of the Gulf of Aqaba in the remote southern desert region of the Sinai peninsula has revealed the presence of the registered drug metformin (4). However, analysis of the C-14 content revealed the drug to be an anthropogenic contaminant. Consequently, natural product researchers should be aware that compounds isolated from plants might originate from environmental contamination rather than biosynthesis. The new natural product N-(4-hydroxyphenylethyl)-alpha-chloroferuloylamide was isolated as a mixture of the E and Z isomers along with a number of other well-established secondary metabolites.
类型	Article
语种	英语
国家	Denmark ; Egypt
收录类别	SCI-E
WOS记录号	WOS:000414234400031
WOS关键词	OCCURRING ORGANOHALOGEN COMPOUNDS ; NATURAL-PRODUCTS ; DRUG METFORMIN ; TRAMADOL ; AGENTS ; DERIVATIVES ; FLAVONOIDS ; PLANTS
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/200696
作者单位	1.Univ Copenhagen, Dept Drug Design & Pharmacol, DK-2100 Copenhagen O, Denmark; 2.Natl Res Ctr, Chem Tannins Dept, Cairo 12622, Egypt; 3.Menoufia Univ, Chem Dept, Shibin Al Kawm 32861, El Menoufia, Egypt; 4.Aarhus Univ, Dept Phys & Astron, DK-8000 Aarhus C, Denmark; 5.Desert Res Ctr, Med & Aromat Plants Dept, Cairo 11753, Egypt
推荐引用方式 GB/T 7714	Hassan, Ahmed R.,El-Kousy, Salah M.,El-Toumy, Sayed A.,et al. Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula[J],2017,80(10):2830-2834.
APA	Hassan, Ahmed R..,El-Kousy, Salah M..,El-Toumy, Sayed A..,Frydenyang, Karla.,Truong Thanh Tung.,...&Christensen, Soren Bragger.(2017).Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula.JOURNAL OF NATURAL PRODUCTS,80(10),2830-2834.
MLA	Hassan, Ahmed R.,et al."Metformin, an Anthropogenic Contaminant of Seidlitzia rosmarinus Collected in a Desert Region near the Gulf of Aqaba, Sinai Peninsula".JOURNAL OF NATURAL PRODUCTS 80.10(2017):2830-2834.