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DOI10.3390/genes8100262
Complete Mitochondrial Genome Sequencing of a Burial from a Romano-Christian Cemetery in the Dakhleh Oasis, Egypt: Preliminary Indications
Molto, J. Eldon1; Loreille, Odile2; Mallott, Elizabeth K.3; Malhi, Ripan S.4,5; Fast, Spence2; Daniels-Higginbotham, Jennifer2; Marshall, Charla2; Parr, Ryan6
通讯作者Molto, J. Eldon
来源期刊GENES
ISSN2073-4425
出版年2017
卷号8期号:10
英文摘要

The curse of ancient Egyptian DNA was lifted by a recent study which sequenced the mitochondrial genomes (mtGenome) of 90 ancient Egyptians from the archaeological site of Abusir el-Meleq. Surprisingly, these ancient inhabitants were more closely related to those from the Near East than to contemporary Egyptians. It has been accepted that the timeless highway of the Nile River seeded Egypt with African genetic influence, well before pre-Dynastic times. Here we report on the successful recovery and analysis of the complete mtGenome from a burial recovered from a remote Romano-Christian cemetery, Kellis 2 (K2). K2 serviced the ancient municipality of Kellis, a village located in the Dakhleh Oasis in the southwest desert in Egypt. The data were obtained by high throughput sequencing (HTS) performed independently at two ancient DNA facilities (Armed Forces DNA Identification Laboratory, Dover, DE, USA and Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL, USA). These efforts produced concordant haplotypes representing a U1a1a haplogroup lineage. This result indicates that Near Eastern maternal influence previously identified at Abusir el-Meleq was also present further south, in ancient Kellis during the Romano-Christian period.


英文关键词Dakhleh Oasis mitochondrial genome Egypt high throughput sequencing U1a1a haplogroup ancient DNA
类型Article
语种英语
国家Canada ; USA
收录类别SCI-E
WOS记录号WOS:000414862300027
WOS关键词READ ALIGNMENT ; DNA ; CAUCASUS ; SAMPLES
WOS类目Genetics & Heredity
WOS研究方向Genetics & Heredity
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/199149
作者单位1.Western Univ, Dept Anthropol, London, ON N6A 3K7, Canada;
2.Armed Forces Med Examiner Syst, Armed Forces DNA Identificat Lab AFMES AFDIL, Dover, DE 19902 USA;
3.Northwestern Univ, Dept Anthropol, Evanston, IL 60208 USA;
4.Univ Illinois, Dept Anthropol, 109 Davenport Hall,607 S Mathews Ave, Urbana, IL 61801 USA;
5.Univ Illinois, Carl R Woese Inst Genom Biol, Urbana, IL 61801 USA;
6.Lakehead Univ, Dept Anthropol, Thunder Bay, ON P7B 5E1, Canada
推荐引用方式
GB/T 7714
Molto, J. Eldon,Loreille, Odile,Mallott, Elizabeth K.,et al. Complete Mitochondrial Genome Sequencing of a Burial from a Romano-Christian Cemetery in the Dakhleh Oasis, Egypt: Preliminary Indications[J],2017,8(10).
APA Molto, J. Eldon.,Loreille, Odile.,Mallott, Elizabeth K..,Malhi, Ripan S..,Fast, Spence.,...&Parr, Ryan.(2017).Complete Mitochondrial Genome Sequencing of a Burial from a Romano-Christian Cemetery in the Dakhleh Oasis, Egypt: Preliminary Indications.GENES,8(10).
MLA Molto, J. Eldon,et al."Complete Mitochondrial Genome Sequencing of a Burial from a Romano-Christian Cemetery in the Dakhleh Oasis, Egypt: Preliminary Indications".GENES 8.10(2017).
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