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Modern climate in the Andes is characterized by strong N-S decreasing trends in precipitation rates. Here we use stratigraphic records to show that this pattern has been established since as early as 12-11 Ma, at least on the western Andean margin of Northern Chile. The stratigraphic architecture on the western Andean margin documents a transition between 19 degrees-20 degrees S latitude where matrix-supported debris flow deposits shift to fluvial conglomerates between 12-11 Ma. The deposition of fluvial sediments has been maintained to the present north of 19 degrees-20 degrees S, while the occurrence of post 11 Ma aeolian sand, matrix supported breccias with conglomerate interbeds south of these latitudes implies ongoing sedimentation with less water and thus under drier conditions. We relate these changes to the tectonic development of the Andes. Existing palaeoclimate models suggest that an elevated plateau deflects the Andean jet towards the south, thereby focusing moisture from the equatorial Atlantic to the northeastern flanks of the Altiplano. In addition, the formation of the eastern Andean foothills most likely intercepted moisture transport, and shifted it farther to the east, thereby keeping the western Andean margin dry south of 19 degrees-20 degrees S latitudes. The sedimentological data support a strong linkage between orographic precipitation and stratigraphy whereby central Andean deformation controls the distribution of available moisture on the western flank through a combination of orographic precipitation and deflection of air masses. (C) 2017 Elsevier B.V. All rights reserved.