Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1021/acs.analchem.7b02867 |
Optimization of the Determination Method for Dissolved Cyanobacterial Toxin BMAA in Natural Water | |
Yan, Boyin1; Liu, Zhiquan1; Huang, Rui1; Xu, Yongpeng1; Liu, Dongmei1; Lin, Tsair-Fuh2; Cui, Fuyi1 | |
通讯作者 | Liu, Zhiquan ; Cui, Fuyi |
来源期刊 | ANALYTICAL CHEMISTRY
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ISSN | 0003-2700 |
EISSN | 1520-6882 |
出版年 | 2017 |
卷号 | 89期号:20页码:10991-10998 |
英文摘要 | There is a serious dispute on the existence of beta-N-methylamino-Lalanine (BMAA) in water, which is a neurotcndn that may cause amyotrophic lateral sclerosis/Parkinson’s disease (ALS/PDC) and Alzheimer’ disease. It is believed that a reliable and sensitive analytical method for the determination of BMAA is urgently required to resolve this dispute. In the present study, the solid phase extraction (SPE) procedure and the analytical method for dissolved BMAA in water were investigated and optimized. The results showed both derivatized and underivatized methods were qualified for the measurement of BMAA and its isomer in natural water, and the limit of detection and the precision of the two methods were comparable. Cartridge characteristics and SPE conditions could greatly affect the SPE performance, and the competition of natural organic matter is the primary factor causing the low recovery of BMAA, which was reduced from approximately 90% in pure water to 38.11% in natural water. The optimized SPE method for BMAA was a combination of rinsed SPE cartridges, controlled loading/elution rates and elution solution, evaporation at 55 degrees C, reconstitution of a solution mixture, and filtration by polyvinylidene fluoride membrane. This optimized method achieved > 88% recovery of BMAA in both algal solution and river water. The developed method can provide an efficient way to evaluate the actual concentration levels of BMAA in actual water environments and drinking water systems. |
类型 | Article |
语种 | 英语 |
国家 | Peoples R China ; Taiwan |
收录类别 | SCI-E |
WOS记录号 | WOS:000413392500048 |
WOS关键词 | METHYLAMINO-L-ALANINE ; TANDEM MASS-SPECTROMETRY ; 2,4-DIAMINOBUTYRIC ACID DAB ; NEUROTOXIC AMINO-ACID ; NEURODEGENERATIVE DISEASE ; INTRAPARTICLE DIFFUSION ; DESERT ENVIRONMENTS ; CHAMORRO PEOPLE ; FRESH-WATER ; PERFORMANCE |
WOS类目 | Chemistry, Analytical |
WOS研究方向 | Chemistry |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/197285 |
作者单位 | 1.Harbin Inst Technol, State Key Lab Urban Water Resource & Environm, Harbin 150090, Heilongjiang, Peoples R China; 2.Natl Cheng Kung Univ, Dept Environm Engn, Tainan 701, Taiwan |
推荐引用方式 GB/T 7714 | Yan, Boyin,Liu, Zhiquan,Huang, Rui,et al. Optimization of the Determination Method for Dissolved Cyanobacterial Toxin BMAA in Natural Water[J],2017,89(20):10991-10998. |
APA | Yan, Boyin.,Liu, Zhiquan.,Huang, Rui.,Xu, Yongpeng.,Liu, Dongmei.,...&Cui, Fuyi.(2017).Optimization of the Determination Method for Dissolved Cyanobacterial Toxin BMAA in Natural Water.ANALYTICAL CHEMISTRY,89(20),10991-10998. |
MLA | Yan, Boyin,et al."Optimization of the Determination Method for Dissolved Cyanobacterial Toxin BMAA in Natural Water".ANALYTICAL CHEMISTRY 89.20(2017):10991-10998. |
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