Arid
DOI10.1590/S0100-736X2016000900014
Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil
Silva, Jardel B.1; Costa, Kizzy M. F. M.1; Coelho, Wesley A. C.2; Paiva, Kaliane A. R.1; Costa, Geysa A. V.1; Salatino, Antonio3; Freitas, Carlos I. A.1; Batista, Jael S.1
通讯作者Silva, Jardel B.
来源期刊PESQUISA VETERINARIA BRASILEIRA
ISSN0100-736X
EISSN1678-5150
出版年2016
卷号36期号:9页码:874-880
英文摘要

This study aimed to evaluate the chemical composition and therapeutic potential of the hydroalcoholic extract of geopropolis produced by bees Plebeia aff.flavocincta in Rio Grande do Norte semi-arid. Eight samples (A-H) were submitted to the quantification of total phenols and flavonoid content and evaluation of the antioxidant activity by DPPH method (2,2-diphenyl-1-picryl-hydrazyl). Additionally, antibacterial activities were investigated by agar diffusion method, and healing process by inducing experimental surgical wounds in Rattus norvegicus Berkenhout, 1769, Wistar line, and treated with the geopropolis-based cream. Two samples (F and G) have stood out by presenting high values of total phenols and flavonoids. The antioxidant capacity of over 90% was observed in five samples. The extracts were considered effective in relation to antibacterial activity since of the eight samples, five promoted the formation of inhibition zones >= 9mm above all strains tested. Two samples (D and G) have stood out over the other for presenting excellent results since it promoted the formation of inhibition zones for Staphylococcus epidermidis and Escherichia coli exceeding statistically to the values of the antibiotic controls when the concentration was 100%. Samples A and C have provided, respectively, that the formation of inhibition zones were not significantly different than the halos produced by antibiotics controls at all concentrations tested for Escherichia coil and Staphylococcus aureus. The analysis of the healing process from the clinical, macroscopic and histological points of view, allowed to conclude that the use of geopropolis-based cream had a positive influence on the healing of experimental skin wounds by promoting less intense inflammatory reaction and healing faster from wounds in the control group.


英文关键词Phenols flavonoids geopropolis Plebeia aff. flavocincta stingless bees therapeutic potential semiarid region Brazil
类型Article
语种葡萄牙语
国家Brazil
收录类别SCI-E
WOS记录号WOS:000391438400014
WOS关键词ANTIOXIDANT ACTIVITY ; PLANT-EXTRACTS ; STINGLESS BEES ; PROPOLIS ; ANTIBACTERIAL
WOS类目Veterinary Sciences
WOS研究方向Veterinary Sciences
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/195419
作者单位1.Univ Fed Rural Semiarido Utersa, Dept Ciencias Anim, Av Francisco Mota, BR-59625900 Mossoro, RN, Brazil;
2.Fac Enfermagem Nova Esperanca Mossoro Facene, Av Presidente Dutra, BR-59628000 Mossoro, RN 59628000, Brazil;
3.Univ Sao Paulo, Dept Bot, Rua Matao, BR-05508090 Sao Paulo, SP, Brazil
推荐引用方式
GB/T 7714
Silva, Jardel B.,Costa, Kizzy M. F. M.,Coelho, Wesley A. C.,et al. Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil[J],2016,36(9):874-880.
APA Silva, Jardel B..,Costa, Kizzy M. F. M..,Coelho, Wesley A. C..,Paiva, Kaliane A. R..,Costa, Geysa A. V..,...&Batista, Jael S..(2016).Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil.PESQUISA VETERINARIA BRASILEIRA,36(9),874-880.
MLA Silva, Jardel B.,et al."Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil".PESQUISA VETERINARIA BRASILEIRA 36.9(2016):874-880.
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