Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1590/S0100-736X2016000900014 |
Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil | |
Silva, Jardel B.1; Costa, Kizzy M. F. M.1; Coelho, Wesley A. C.2; Paiva, Kaliane A. R.1; Costa, Geysa A. V.1; Salatino, Antonio3; Freitas, Carlos I. A.1; Batista, Jael S.1 | |
通讯作者 | Silva, Jardel B. |
来源期刊 | PESQUISA VETERINARIA BRASILEIRA
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ISSN | 0100-736X |
EISSN | 1678-5150 |
出版年 | 2016 |
卷号 | 36期号:9页码:874-880 |
英文摘要 | This study aimed to evaluate the chemical composition and therapeutic potential of the hydroalcoholic extract of geopropolis produced by bees Plebeia aff.flavocincta in Rio Grande do Norte semi-arid. Eight samples (A-H) were submitted to the quantification of total phenols and flavonoid content and evaluation of the antioxidant activity by DPPH method (2,2-diphenyl-1-picryl-hydrazyl). Additionally, antibacterial activities were investigated by agar diffusion method, and healing process by inducing experimental surgical wounds in Rattus norvegicus Berkenhout, 1769, Wistar line, and treated with the geopropolis-based cream. Two samples (F and G) have stood out by presenting high values of total phenols and flavonoids. The antioxidant capacity of over 90% was observed in five samples. The extracts were considered effective in relation to antibacterial activity since of the eight samples, five promoted the formation of inhibition zones >= 9mm above all strains tested. Two samples (D and G) have stood out over the other for presenting excellent results since it promoted the formation of inhibition zones for Staphylococcus epidermidis and Escherichia coli exceeding statistically to the values of the antibiotic controls when the concentration was 100%. Samples A and C have provided, respectively, that the formation of inhibition zones were not significantly different than the halos produced by antibiotics controls at all concentrations tested for Escherichia coil and Staphylococcus aureus. The analysis of the healing process from the clinical, macroscopic and histological points of view, allowed to conclude that the use of geopropolis-based cream had a positive influence on the healing of experimental skin wounds by promoting less intense inflammatory reaction and healing faster from wounds in the control group. |
英文关键词 | Phenols flavonoids geopropolis Plebeia aff. flavocincta stingless bees therapeutic potential semiarid region Brazil |
类型 | Article |
语种 | 葡萄牙语 |
国家 | Brazil |
收录类别 | SCI-E |
WOS记录号 | WOS:000391438400014 |
WOS关键词 | ANTIOXIDANT ACTIVITY ; PLANT-EXTRACTS ; STINGLESS BEES ; PROPOLIS ; ANTIBACTERIAL |
WOS类目 | Veterinary Sciences |
WOS研究方向 | Veterinary Sciences |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/195419 |
作者单位 | 1.Univ Fed Rural Semiarido Utersa, Dept Ciencias Anim, Av Francisco Mota, BR-59625900 Mossoro, RN, Brazil; 2.Fac Enfermagem Nova Esperanca Mossoro Facene, Av Presidente Dutra, BR-59628000 Mossoro, RN 59628000, Brazil; 3.Univ Sao Paulo, Dept Bot, Rua Matao, BR-05508090 Sao Paulo, SP, Brazil |
推荐引用方式 GB/T 7714 | Silva, Jardel B.,Costa, Kizzy M. F. M.,Coelho, Wesley A. C.,et al. Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil[J],2016,36(9):874-880. |
APA | Silva, Jardel B..,Costa, Kizzy M. F. M..,Coelho, Wesley A. C..,Paiva, Kaliane A. R..,Costa, Geysa A. V..,...&Batista, Jael S..(2016).Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil.PESQUISA VETERINARIA BRASILEIRA,36(9),874-880. |
MLA | Silva, Jardel B.,et al."Quantification of phenols, total flavonoids and pharmacological activities of geopropolis Plebeia aff. flavocincta of Rio Grande do Norte, Brazil".PESQUISA VETERINARIA BRASILEIRA 36.9(2016):874-880. |
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