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Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan
Alam, Muhammad Khurshid1; Ahmed, Saeed2; Anjum, Shazia1; Akram, Muhammad3; Shah, Syed Muhammad Ali4; Wariss, Hafiz Muhammad; Usmanghani, Khan5
通讯作者Akram, Muhammad
来源期刊PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
ISSN1011-601X
出版年2016
卷号29期号:2页码:529-533
英文摘要

Traditional herbal healers "Hakims" use various plants of the Cholistan desert, Pakistan for treating a number of infectious and non-infectious diseases. However, there has never been a scientific validation of these plant-based therapeutics. We compared the antipyretic effect of Echinops echinatus, Alhagi maurorum, Fagonia cretica, Cymbopogon jwarancusa and Panicum turgidum in animal model. These plants were used to reduce,E.coli lysate induced pyrexia in rabbits. There were five groups of rabbits having five rabbits in each group. Among these five groups, three received various doses of experimental treatment, paracetamol was given to fourth group known as positive control. The fifth group of animals served as negative control and received no treatment. Ethanol extracts of Fagonia cretica (500mg/kg), Panicum turgidum (500mg/kg and 750mg/kg), Alhagi maurorum (500 and 750mg/kg), Cymbopogon jwarancusa (250mg/kg) and Echinops echinatus (750mg/kg) showed significant antipyretic effects when compared with controls and experimental counterparts. These results revealed that ethanol extracts of the plants evaluated in this study have dose dependent antipyretic activity. Further detailed screening of these plant species is recommended.


英文关键词Escherichia coli Cholistan desert analgesic anti-inflammatory prostaglandin E. coli induced pyrexia traditional medicine
类型Article
语种英语
国家Pakistan
收录类别SCI-E
WOS记录号WOS:000374800500023
WOS类目Pharmacology & Pharmacy
WOS研究方向Pharmacology & Pharmacy
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/195299
作者单位1.Islamia Univ Bahawalpur, Cholistan Inst Desert Studies, Bahawalpur, Pakistan;
2.Univ Sargodha, Univ Coll Agr, Sargodha, Pakistan;
3.Univ Poonch, Dept Eastern Med & Surg, Fac Med & Hlth Sci, Rawalakot, Azad Kashmir, Pakistan;
4.Govt Coll Univ, Dept Eastern Med & Surg, Directorate Med Sci, Faisalabad, Pakistan;
5.Hamdard Univ, Fac Eastern Med, Karachi, Pakistan
推荐引用方式
GB/T 7714
Alam, Muhammad Khurshid,Ahmed, Saeed,Anjum, Shazia,et al. Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan[J],2016,29(2):529-533.
APA Alam, Muhammad Khurshid.,Ahmed, Saeed.,Anjum, Shazia.,Akram, Muhammad.,Shah, Syed Muhammad Ali.,...&Usmanghani, Khan.(2016).Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan.PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES,29(2),529-533.
MLA Alam, Muhammad Khurshid,et al."Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan".PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES 29.2(2016):529-533.
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