Knowledge Resource Center for Ecological Environment in Arid Area
Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan | |
Alam, Muhammad Khurshid1; Ahmed, Saeed2; Anjum, Shazia1; Akram, Muhammad3; Shah, Syed Muhammad Ali4; Wariss, Hafiz Muhammad; Usmanghani, Khan5 | |
通讯作者 | Akram, Muhammad |
来源期刊 | PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
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ISSN | 1011-601X |
出版年 | 2016 |
卷号 | 29期号:2页码:529-533 |
英文摘要 | Traditional herbal healers "Hakims" use various plants of the Cholistan desert, Pakistan for treating a number of infectious and non-infectious diseases. However, there has never been a scientific validation of these plant-based therapeutics. We compared the antipyretic effect of Echinops echinatus, Alhagi maurorum, Fagonia cretica, Cymbopogon jwarancusa and Panicum turgidum in animal model. These plants were used to reduce,E.coli lysate induced pyrexia in rabbits. There were five groups of rabbits having five rabbits in each group. Among these five groups, three received various doses of experimental treatment, paracetamol was given to fourth group known as positive control. The fifth group of animals served as negative control and received no treatment. Ethanol extracts of Fagonia cretica (500mg/kg), Panicum turgidum (500mg/kg and 750mg/kg), Alhagi maurorum (500 and 750mg/kg), Cymbopogon jwarancusa (250mg/kg) and Echinops echinatus (750mg/kg) showed significant antipyretic effects when compared with controls and experimental counterparts. These results revealed that ethanol extracts of the plants evaluated in this study have dose dependent antipyretic activity. Further detailed screening of these plant species is recommended. |
英文关键词 | Escherichia coli Cholistan desert analgesic anti-inflammatory prostaglandin E. coli induced pyrexia traditional medicine |
类型 | Article |
语种 | 英语 |
国家 | Pakistan |
收录类别 | SCI-E |
WOS记录号 | WOS:000374800500023 |
WOS类目 | Pharmacology & Pharmacy |
WOS研究方向 | Pharmacology & Pharmacy |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/195299 |
作者单位 | 1.Islamia Univ Bahawalpur, Cholistan Inst Desert Studies, Bahawalpur, Pakistan; 2.Univ Sargodha, Univ Coll Agr, Sargodha, Pakistan; 3.Univ Poonch, Dept Eastern Med & Surg, Fac Med & Hlth Sci, Rawalakot, Azad Kashmir, Pakistan; 4.Govt Coll Univ, Dept Eastern Med & Surg, Directorate Med Sci, Faisalabad, Pakistan; 5.Hamdard Univ, Fac Eastern Med, Karachi, Pakistan |
推荐引用方式 GB/T 7714 | Alam, Muhammad Khurshid,Ahmed, Saeed,Anjum, Shazia,et al. Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan[J],2016,29(2):529-533. |
APA | Alam, Muhammad Khurshid.,Ahmed, Saeed.,Anjum, Shazia.,Akram, Muhammad.,Shah, Syed Muhammad Ali.,...&Usmanghani, Khan.(2016).Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan.PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES,29(2),529-533. |
MLA | Alam, Muhammad Khurshid,et al."Evaluation of antipyretic activity of some medicinal plants from Cholistan desert Pakistan".PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES 29.2(2016):529-533. |
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