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Zebra-tailed Lizards (Callisaurus draconoides) dwell on sandy soils in a variety of arid habitats. They have large home ranges and do not aggressively defend core areas. In May and June of 2000, I studied the home ranges of Zebra-tailed Lizards in Joshua Tree National Park, California, USA, to determine whether individuals share space through overlapping home ranges. I tested the hypothesis that patterns of space use would vary by sex, age, desert, or study site. I could not calculate estimates of home-range area for 63% of the lizards observed due to their transient nature in the study sites. For those lizards resident in the sites, my findings support a correlation between home-range area and body size, with no variation by sex, age, desert, or study site. Male and female lizards exhibited similar proportions of home-range area overlap; however, males overlapped greater numbers of females than did females. Analyses did not reveal differences in the pattern of space use relating to age, desert, or by site; however, lizards occupying a narrow wash had significantly more home range overlap than those in broad washes, despite home-range area being similar across study sites. Males and females partitioned space differently, and it may be that when space is shared, it is partitioned temporally, with individuals using the space at different times.