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DOI | 10.1016/j.aller.2015.01.010 |
Amelioration of some immunological disorders caused by the faeces of the dominant true house dust mites in El-Minia Governorate, Egypt | |
Abdel-Salam, Bahaa K. A.1,2; Shoker, Nagiba I. A.1; Mohamad, Ahmed M. R.1 | |
通讯作者 | Abdel-Salam, Bahaa K. A. |
来源期刊 | ALLERGOLOGIA ET IMMUNOPATHOLOGIA
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ISSN | 0301-0546 |
EISSN | 1578-1267 |
出版年 | 2016 |
卷号 | 44期号:1页码:23-31 |
英文摘要 | Background: House dust mites (HDMs) faeces are the main factor involved in respiratory disorder. The true HDMs, Dermatophagoides pteronyssinus and D. farinae, detected in the samples collected from the house dust are the most important causes of allergic disorders such as asthma. Objective: The aim of this investigation was to study the curcuma and karkade amelioration of the allergenic immunological disorder, especially some cytokines, IgE and ROS, caused by the faeces of the dominant true HDM, D. pteronyssinus and D. farinae in valley and desert houses in EL-Minia Governorate, respectively. Methods: HDM cultures, faeces isolation, plant extraction and ELISA techniques were used. Male albino rats were classified into control, inhaled, and treated groups. Results: The present immunological study on the dominant allergenic true HDMs, D. pteronyssinus and D. farinae, revealed that significantly higher serum levels of TNF-alpha, IL-1 beta, IL-4, IL-13 and IgE were found in rats treated with both D. pteronyssinus and D. farinae faeces than the other groups. In addition, statistical analysis of ROS data showed significant difference between the curcuma- and karkade-treated groups and either the control or the faeces-treated groups (P < 0.05). Conclusions: Some immunological disturbances caused by repeated exposure to the faeces of two dominant allergenic true HDM species (D. pteronyssinus and D. farinae) in the valley and desert houses could be ameliorated by curcuma and karkade. (C) 2014 SEICAP. Published by Elsevier Espana, S.L.U. All rights reserved. |
英文关键词 | HDMs TNF-alpha IL-4 IL-1 beta IL-13 IgE and ROS |
类型 | Article |
语种 | 英语 |
国家 | Egypt ; Saudi Arabia |
收录类别 | SCI-E |
WOS记录号 | WOS:000369047300005 |
WOS关键词 | NECROSIS-FACTOR-ALPHA ; CELLS IN-VITRO ; ALLERGEN CHALLENGE ; ATOPIC ASTHMA ; IGE ; INTERLEUKIN-4 ; RECEPTOR ; EXPRESSION ; IL-4 ; HYPERREACTIVITY |
WOS类目 | Allergy ; Immunology |
WOS研究方向 | Allergy ; Immunology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/191198 |
作者单位 | 1.Menia Univ, Dept Zool, Fac Sci, El Minia 61519, Egypt; 2.Shaqra Univ, Dept Biol, Coll Sci & Humanities Quwiaya, Shaqra 11961, Saudi Arabia |
推荐引用方式 GB/T 7714 | Abdel-Salam, Bahaa K. A.,Shoker, Nagiba I. A.,Mohamad, Ahmed M. R.. Amelioration of some immunological disorders caused by the faeces of the dominant true house dust mites in El-Minia Governorate, Egypt[J],2016,44(1):23-31. |
APA | Abdel-Salam, Bahaa K. A.,Shoker, Nagiba I. A.,&Mohamad, Ahmed M. R..(2016).Amelioration of some immunological disorders caused by the faeces of the dominant true house dust mites in El-Minia Governorate, Egypt.ALLERGOLOGIA ET IMMUNOPATHOLOGIA,44(1),23-31. |
MLA | Abdel-Salam, Bahaa K. A.,et al."Amelioration of some immunological disorders caused by the faeces of the dominant true house dust mites in El-Minia Governorate, Egypt".ALLERGOLOGIA ET IMMUNOPATHOLOGIA 44.1(2016):23-31. |
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