干旱区生态环境知识资源中心(Arid): Molecular characterization of RNA binding motif protein 3 (RBM3) gene from Pashmina goat

Arid

DOI	10.1016/j.rvsc.2014.11.016
	Molecular characterization of RNA binding motif protein 3 (RBM3) gene from Pashmina goat
	Zargar, Ruby; Urwat, Uneeb; Malik, Firdose; Shah, Riaz A.; Bhat, M. H.; Naykoo, Niyaz A.; Khan, Firdous; Khan, H. M.; Ahmed, Syed Mudasir; Vijh, Ramesh Kumar; Ganai, Nazir A.
通讯作者	Ganai, Nazir A.
来源期刊	RESEARCH IN VETERINARY SCIENCE
ISSN	0034-5288
EISSN	1532-2661
出版年	2015
卷号	98 页码:51-58
英文摘要	Pashmina goat inhabits the high altitude cold arid desert of Ladakh, India. This goat is known for its finest and costliest under fiber. Though the under fiber may be a part of its complex thermoregulation mechanism, the genetics of its adaptability under cold conditions is not known. As an attempt to understand its adaptive genetics, and the role of RNA-binding proteins at the cellular response, this study was conducted to characterize the RBM3 gene in Pashmina goat and its expression during hypothermia. The ORF of Pashmina RBM3 gene was 273 bp. Phylogenetic analysis revealed that Pashmina RBM3 is closely related to Bos taurus RBM3. Pashmina RBM3 was characterized by comparative modeling studies. The final 3-D model contained two alpha-helices and four beta-sheets. qRT-PCR data showed that Pashmina RBM3 gene expression was significantly higher (P < 0.05) at moderate (30 degrees C) hypothermic stress conditions as compared with deep (15 degrees C) hypothermia. (C) 2014 Elsevier Ltd. All rights reserved.
英文关键词	Pashmina Hypothermia RNA binding motif protein 3 Expression analysis Comparative modeling
类型	Article
语种	英语
国家	India
收录类别	SCI-E
WOS记录号	WOS:000349582300010
WOS关键词	COLD-SHOCK PROTEIN ; MESSENGER-RNA ; EXPRESSION ; NUCLEAR ; CELLS ; TRANSLATION ; HYPOTHERMIA ; FAMILY ; DOMAIN
WOS类目	Veterinary Sciences
WOS研究方向	Veterinary Sciences
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/190234
作者单位	SKUASTK, Div Anim Biotechnol, Jammu, India
推荐引用方式 GB/T 7714	Zargar, Ruby,Urwat, Uneeb,Malik, Firdose,et al. Molecular characterization of RNA binding motif protein 3 (RBM3) gene from Pashmina goat[J],2015,98:51-58.
APA	Zargar, Ruby.,Urwat, Uneeb.,Malik, Firdose.,Shah, Riaz A..,Bhat, M. H..,...&Ganai, Nazir A..(2015).Molecular characterization of RNA binding motif protein 3 (RBM3) gene from Pashmina goat.RESEARCH IN VETERINARY SCIENCE,98,51-58.
MLA	Zargar, Ruby,et al."Molecular characterization of RNA binding motif protein 3 (RBM3) gene from Pashmina goat".RESEARCH IN VETERINARY SCIENCE 98(2015):51-58.