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Dry Land Asia is the largest arid and semi-arid region in the northern hemisphere that suffers from land desertification. Over the period 1982-2011, there were both overall improvement and regional degeneration in the vegetation NDVI. We analyze future climate changes in these area using two ensemble-average methods from CMIP5 data. Bayesian Model Averaging shows a better capability to represent the future climate and less uncertainty represented by the 22-model ensemble than does the Simple Model Average. From 2006 to 2100, the average growing season temperature value will increase by 2.9 degrees C, from 14.4 degrees C to 17.3 degrees C under three climate scenarios (RCP 26, RCP 45 and RCP 85). We then conduct multiple regression analysis between climate changes compiled from the Climate Research Unit database and vegetation greenness from the GIMMS NDVI3g dataset. There is a general acceleration in the desertification trend under the RCP 85 scenario in middle and northern part of Middle Asia, northwestern China except Xinjiang and the Mongolian Plateau (except the middle part). The RCP 85 scenario shows a more severe desertification trend than does RCP 26. Desertification in dry land Asia, particularly in the regions highlighted in this study, calls for further investigation into climate change impacts and adaptations.