Arid
DOI10.1016/j.jinsphys.2015.02.010
Drosha, Dicer-1 and Argonaute-1 in the desert locust: Phylogenetic analyses, transcript profiling and regulation during phase transition and feeding
Wynant, Niels; Santos, Dulce; Subramanyam, Sudheendra Hebbar; Verlinden, Heleen; Broeck, Jozef Vanden
通讯作者Wynant, Niels
来源期刊JOURNAL OF INSECT PHYSIOLOGY
ISSN0022-1910
EISSN1879-1611
出版年2015
卷号75页码:20-29
英文摘要

In this article, we identify and characterise the miRNA machinery components Drosha, Dicer-1 and Argonaute-1 of the desert locust. By means of phylogenetic analyses, we reveal important insights in the evolutionary context of these components. Our data illustrate that insect Argonaute-1 proteins form a monophyletic group with ALG-1 and ALG-2 of Caenorhabditis elegans and with the four (non-Piwi) Argonaute proteins present in humans. On the other hand, humans apparently lack clear homologues of the insect Argonaute-2 proteins. In addition, we demonstrate that drosha, dicer-1 and argonaute-1 display wide transcript tissue-distribution in adult desert locusts, and that during locust phase transition and feeding of starved locusts the expression levels of the miRNA pathway are regulated at the transcript level. (C) 2015 Elsevier Ltd. All rights reserved.


英文关键词Micro RNA RNA interference (RNAi) Schistocerca gregaria Insect Orthoptera Gregarisation Phenotypic plasticity Piwi Drosha Dicer Argonaute piRNA siRNA dsRNA
类型Article
语种英语
国家Belgium
收录类别SCI-E
WOS记录号WOS:000353739100004
WOS关键词SYSTEMIC RNA INTERFERENCE ; SMALL SILENCING RNAS ; DOUBLE-STRANDED-RNA ; SCHISTOCERCA-GREGARIA ; C-ELEGANS ; MIGRATORY LOCUST ; DISTINCT ROLES ; NEUROPEPTIDE F ; HONEY-BEES ; DROSOPHILA
WOS类目Entomology ; Physiology ; Zoology
WOS研究方向Entomology ; Physiology ; Zoology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/188828
作者单位Katholieke Univ Leuven, Mol Dev Physiol & Signal Transduct, B-3000 Louvain, Belgium
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GB/T 7714
Wynant, Niels,Santos, Dulce,Subramanyam, Sudheendra Hebbar,et al. Drosha, Dicer-1 and Argonaute-1 in the desert locust: Phylogenetic analyses, transcript profiling and regulation during phase transition and feeding[J],2015,75:20-29.
APA Wynant, Niels,Santos, Dulce,Subramanyam, Sudheendra Hebbar,Verlinden, Heleen,&Broeck, Jozef Vanden.(2015).Drosha, Dicer-1 and Argonaute-1 in the desert locust: Phylogenetic analyses, transcript profiling and regulation during phase transition and feeding.JOURNAL OF INSECT PHYSIOLOGY,75,20-29.
MLA Wynant, Niels,et al."Drosha, Dicer-1 and Argonaute-1 in the desert locust: Phylogenetic analyses, transcript profiling and regulation during phase transition and feeding".JOURNAL OF INSECT PHYSIOLOGY 75(2015):20-29.
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