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Pugionium cornutum (L.) Gaertn. (PCG) is a desert plant with edible and medicinal value. The contents of proximate composition, amino acids and vitamins of fresh and pickled PCG were analyzed. PCG is rich in dietary fiber, protein and vitamins. PCG is a dietary source of potassium and calcium, with low levels of fat and sugar. PCG contains all the 18 hydrolyzed amino acids. Pickled PCG protein is a high quality protein. A large quantity of vitamins are lost during the pickling process. The type and number of mice dejections, gastric emptying and intestinal propulsion were investigated using the water extract of fresh and pickled PCG (WEFP and WEPP) to determine their gastrointestinal prokinetic efficacy. The low-dose WEFP and WEPP promoted the gastrointestinal dynamics and the WEFP and WEPP promoted gastrointestinal activity and act as nonviolent drugs. The results indicate that PCG has great potential as a new functional food source. (C) 2015 Elsevier Ltd. All rights reserved.