干旱区生态环境知识资源中心(Arid): Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8

Arid

DOI	10.1155/2015/583293
	Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8
	Watanabe, Masanari 1; Noma, Hisashi 2; Kurai, Jun 1; Sano, Hiroyuki 3; Saito, Rumiko 4; Abe, Satoshi 5; Kimura, Yutaka 5; Aiba, Setsuya 5; Oshimura, Mitsuo 6; Yamasaki, Akira 1; Shimizu, Eiji 1
通讯作者	Watanabe, Masanari
来源期刊	BIOMED RESEARCH INTERNATIONAL
ISSN	2314-6133
EISSN	2314-6141
出版年	2015
英文摘要	The objective of the study was to investigate the influence of Asian dust storms (ADS) on pulmonary function of school children and the relationship of this effect with interleukin-8. Morning peak expiratory flow (PEF) was measured daily in 399 children from April to May 2012 and in 384 of these children from March to May 2013. The data were analyzed for an association between ADS events and PEF by linear mixed models. Interleukin-8 transcriptional activity was assessed in THP-G8 cells stimulated by airborne particles collected on ADS days. Seven ADS days were identified: April 23 and 24, 2012; March 8 to 10, 2013; and March 19 and 20, 2013. Changes in PEF after ADS exposure were -8.17 L/min (95% confidence interval, -11.40 to -4.93) in 2012 and -1.17 L/min (-4.07 to 1.74) in 2013, and there was a significant difference between 2012 and 2013. Interleukin-8 transcriptional activity was significantly higher in 2012 at 10.6 +/- 2.9-fold compared to 3.7 +/- 0.4 in March 8 to 10, 2013, and 2.3 +/- 0.2 in March 19 and 20, 2013. The influence of ADS events on pulmonary function of children differs with each ADS event and may be related to interleukin-8 production.
类型	Article
语种	英语
国家	Japan
收录类别	SCI-E
WOS记录号	WOS:000354304800001
WOS关键词	PEAK EXPIRATORY FLOW ; RESPIRATORY SYMPTOMS ; AIR-POLLUTION ; STORM EVENTS ; INFLAMMATORY RESPONSE ; PARTICULATE MATTER ; DAILY MORTALITY ; SOURCE REGIONS ; SAND DUST ; ASTHMA
WOS类目	Biotechnology & Applied Microbiology ; Medicine, Research & Experimental
WOS研究方向	Biotechnology & Applied Microbiology ; Research & Experimental Medicine
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/186264
作者单位	1.Tottori Univ Hosp, Dept Resp Med & Rheumatol, Yonago, Tottori 6838504, Japan; 2.Inst Stat Math, Dept Data Sci, Tokyo 1908562, Japan; 3.Kinki Univ, Dept Resp Med & Allergol, Fac Med, Osakasayama 5898511, Japan; 4.Tohoku Univ, Tohoku Med Megabank Org, Dept Integrat Genom, Sendai, Miyagi 9808574, Japan; 5.Tottori Univ, Chromosome Engn Res Ctr, Tottori 6838504, Japan; 6.Tohoku Univ, Dept Dermatol, Grad Sch Med, Sendai, Miyagi 9808574, Japan
推荐引用方式 GB/T 7714	Watanabe, Masanari,Noma, Hisashi,Kurai, Jun,et al. Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8[J],2015.
APA	Watanabe, Masanari.,Noma, Hisashi.,Kurai, Jun.,Sano, Hiroyuki.,Saito, Rumiko.,...&Shimizu, Eiji.(2015).Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8.BIOMED RESEARCH INTERNATIONAL.
MLA	Watanabe, Masanari,et al."Decreased Pulmonary Function in School Children in Western Japan after Exposures to Asian Desert Dusts and Its Association with Interleukin-8".BIOMED RESEARCH INTERNATIONAL (2015).