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Molybdenum-bismuth-silver and uranium-fluorine mineralization in the Gabal Gattar area are genetically related. Both are hosted in fractionated and hydrothermally altered A-type granite. While Mo-Bi-Ag ore is hosted in NS striking quartz veins, the U-F mineralization forms batches and micro-veinlets, controlled by NNE to NW trending structures. U was incorporated in late-magmatic hypogene minerals (e.g. zircon and xenotime) and in U-Th-minerals closely associated with fluorite. Molybdenite, native bismuth, galena, chalcopyrite, sphalerite, aikinite "PbCuBiS3", benyite "S-16 (Cu,Ag)(6) Bi7Pb3" and native silver were identified in the quartz veins. Fluid inclusions occur in fluorite (Type-1) associated with U minerals and in quartz (Type-2) from Mo-bearing veins. Type-1 and 2 inclusions homogenize at temperatures between 220 degrees C and 106 degrees C, their salinity ranges from 1.3 to 10 wt.% NaCleq, respectively. F-rich fluids accumulated at the last stage of granite crystallization, extracted ore metals and deposited them in a shallow hydrothermal system. Mo, Bi and Ag precipitated earlier from saline fluids due to cooling, fluid mixing and wallrock sulfidation. U-F minerals precipitated from low-salinity fluids after high input of meteoric water. (c) 2014 Elsevier B.V. All rights reserved.