Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1155/2014/862307 |
An Ensemble-of-Classifiers Based Approach for Early Diagnosis of Alzheimer’s Disease: Classification Using Structural Features of Brain Images | |
Farhan, Saima; Fahiem, Muhammad Abuzar; Tauseef, Huma | |
通讯作者 | Fahiem, Muhammad Abuzar |
来源期刊 | COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE
![]() |
ISSN | 1748-670X |
EISSN | 1748-6718 |
出版年 | 2014 |
英文摘要 | Structural brain imaging is playing a vital role in identification of changes that occur in brain associated with Alzheimer’s disease. This paper proposes an automated image processing based approach for the identification of AD from MRI of the brain. The proposed approach is novel in a sense that it has higher specificity/accuracy values despite the use of smaller feature set as compared to existing approaches. Moreover, the proposed approach is capable of identifying AD patients in early stages. The dataset selected consists of 85 age and gender matched individuals from OASIS database. The features selected are volume of GM, WM, and CSF and size of hippocampus. Three different classification models (SVM, MLP, and J48) are used for identification of patients and controls. In addition, an ensemble of classifiers, based on majority voting, is adopted to overcome the error caused by an independent base classifier. Ten-fold cross validation strategy is applied for the evaluation of our scheme. Moreover, to evaluate the performance of proposed approach, individual features and combination of features are fed to individual classifiers and ensemble based classifier. Using size of left hippocampus as feature, the accuracy achieved with ensemble of classifiers is 93.75%, with 100% specificity and 87.5% sensitivity. |
类型 | Article |
语种 | 英语 |
国家 | Pakistan |
收录类别 | SCI-E |
WOS记录号 | WOS:000344319400001 |
WOS关键词 | MILD COGNITIVE IMPAIRMENT ; PATTERN-CLASSIFICATION ; FEATURE-SELECTION ; MR-IMAGES ; ATROPHY ; PREDICTION ; IMPACT |
WOS类目 | Mathematical & Computational Biology |
WOS研究方向 | Mathematical & Computational Biology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/181455 |
作者单位 | Lahore Coll Women Univ, Dept Comp Sci, Lahore 54000, Pakistan |
推荐引用方式 GB/T 7714 | Farhan, Saima,Fahiem, Muhammad Abuzar,Tauseef, Huma. An Ensemble-of-Classifiers Based Approach for Early Diagnosis of Alzheimer’s Disease: Classification Using Structural Features of Brain Images[J],2014. |
APA | Farhan, Saima,Fahiem, Muhammad Abuzar,&Tauseef, Huma.(2014).An Ensemble-of-Classifiers Based Approach for Early Diagnosis of Alzheimer’s Disease: Classification Using Structural Features of Brain Images.COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE. |
MLA | Farhan, Saima,et al."An Ensemble-of-Classifiers Based Approach for Early Diagnosis of Alzheimer’s Disease: Classification Using Structural Features of Brain Images".COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE (2014). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。