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Southern Africa displays a high topography but paradoxically exhibits tectonic stability and low denudation rates. Here the present controls on denudation in southern Africa are investigated by comparing maximum denudation rates for Karoo dolerite surfaces in the region, determined from the abundances of cosmogenic noble gas nuclides (He-3, Ne-21 and Ar-38) in pyroxenes, with the predictions of a climate-dependent weathering rate model. In general, we find an excellent agreement in the value ranges of both datasets (<4 m/Myr), and interpret this as evidence that present denudation in southern Africa is weathering-limited and climatically influenced due to an apparent absence of significant regional neotectonic uplift. The onset of this geodynamic coupling is unknown but may be of considerable antiquity, thus allowing for the prolonged tenure of southern Africa’s inherited Cretaceous topography. (C) 2013 Elsevier B.V. All rights reserved.