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In this study, the importance of using radar-based rainfall estimation for the modeling of peak flow in poorly gauged basin is highlighted. The hydrological modeling with radar estimated rainfall, takes into account, detailedly, the spatial and temporal variability of the rainfall. The aim of this study was to evaluate the hydrologic simulation of the Escondido river Basin in the hydrometric station 24290 (in Villa de Fuentes, Coahuila, Mexico). The HEC-HMS hydrologic model was used to simulate peak flows using radar-estimated rainfall data. The basin is located in a semi-desert area with the characteristic of ephemeral runoffs and rare extraordinary events recorded during the measurement period (1932 to date). The events analyzed were: June 3, 2003, September 29, 2006 and April 5, 2004, which have been the only important ones of the period of radar data availability. The stage IV precipitation data of NEXRAD radar, located in the military base Launghlin, Texas, were adapted to this case study. To evaluate the results graphical and numerical criteria were used: comparison of hydrographs and the Nash-Sutcliffe efficiency coefficient (E). The results were satisfactory due to coefficient values of Nash-Sutcliffe Efficiency (E) equal with 0.96 in calibration and 0.91 in validation of the model.