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The Rub’ Al-Khali aeolian sand sea of south eastern Saudi Arabia - also known as the Empty Quarter covers an area of 660,000 km(2) and is one of the largest sandy deserts in the world. The region is covered by the latest generation of public-release satellite imagery, which reveal spatially diverse dune patterns characterized by a varied range of dune types, the morphology, scale and orientation of which change systematically from central to marginal dune-field areas where non-aeolian sub-environments become dominant within the overall desert setting. Analysis of geomorphic relationships between dune and interdune sub-environments within 4 regions of the Rub’ Al-Khali reveals predictable spatial changes in dune and interdune morphology, scale and orientation from the centre to the outer margins of dune fields. A quantitative approach is used to characterize the complexity present where large, morphologically complex and compound bedforms gradually give way to smaller and simpler bedform types at dune-field margins. Parameters describing bedform height, spacing, parent morphological type, bedform orientation, lee-slope expression, and wavelength and amplitude of along-crest sinuosity are recorded in a relational database, along with parameters describing interdune size (long-and short-axis dimensions), orientation, and style of connectivity. The spatial rate of change of morphology of aeolian sub-environments is described through a series of empirical relationships. Spatial changes in dune and interdune morphology have enabled the development of a model with which to propose an improved understanding of the sediment system state of the modern Rub’ Al-Khali desert sedimentary system, whereby the generation of an aeolian sediment supply, its availability for aeolian transport and the sand transporting capacity of the wind are each reduced in dune-field margin areas. (C) 2013 Elsevier B.V. All rights reserved.