Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1371/journal.pone.0034458 |
Genome Sequence and Transcriptome Analysis of the Radioresistant Bacterium Deinococcus gobiensis. Insights into the Extreme Environmental Adaptations | |
Yuan, Menglong1,2; Chen, Ming1; Zhang, Wei1; Lu, Wei1; Wang, Jin1; Yang, Mingkun1; Zhao, Peng1; Tang, Ran1; Li, Xinna1; Hao, Yanhua1; Zhou, Zhengfu1; Zhan, Yuhua1; Yu, Haiying1; Teng, Chao1; Yan, Yongliang1; Ping, Shuzhen1; Wang, Yingdian2; Lin, Min1 | |
通讯作者 | Yuan, Menglong |
来源期刊 | PLOS ONE |
ISSN | 1932-6203 |
出版年 | 2012 |
卷号 | 7期号:3 |
英文摘要 | The desert is an excellent model for studying evolution under extreme environments. We present here the complete genome and ultraviolet (UV) radiation-induced transcriptome of Deinococcus gobiensis I-0, which was isolated from the cold Gobi desert and shows higher tolerance to gamma radiation and UV light than all other known microorganisms. Nearly half of the genes in the genome encode proteins of unknown function, suggesting that the extreme resistance phenotype may be attributed to unknown genes and pathways. D. gobiensis also contains a surprisingly large number of horizontally acquired genes and predicted mobile elements of different classes, which is indicative of adaptation to extreme environments through genomic plasticity. High-resolution RNA-Seq transcriptome analyses indicated that 30 regulatory proteins, including several well-known regulators and uncharacterized protein kinases, and 13 noncoding RNAs were induced immediately after UV irradiation. Particularly interesting is the UV irradiation induction of the phrB and recB genes involved in photoreactivation and recombinational repair, respectively. These proteins likely include key players in the immediate global transcriptional response to UV irradiation. Our results help to explain the exceptional ability of D. gobiensis to withstand environmental extremes of the Gobi desert, and highlight the metabolic features of this organism that have biotechnological potential. |
类型 | Article |
语种 | 英语 |
国家 | Peoples R China |
收录类别 | SCI-E |
WOS记录号 | WOS:000304489000112 |
WOS关键词 | RADIATION-RESISTANT BACTERIUM ; ESCHERICHIA-COLI ; IONIZING-RADIATION ; GAMMA-RADIATION ; RADIODURANS ; UV ; PROTEIN ; EXPOSURE ; ENZYME ; REPAIR |
WOS类目 | Multidisciplinary Sciences |
WOS研究方向 | Science & Technology - Other Topics |
来源机构 | 北京师范大学 |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/174510 |
作者单位 | 1.Chinese Acad Agr Sci, Biotechnol Res Inst, Beijing 100193, Peoples R China; 2.Beijing Normal Univ, Coll Life Sci, Beijing 100875, Peoples R China |
推荐引用方式 GB/T 7714 | Yuan, Menglong,Chen, Ming,Zhang, Wei,et al. Genome Sequence and Transcriptome Analysis of the Radioresistant Bacterium Deinococcus gobiensis. Insights into the Extreme Environmental Adaptations[J]. 北京师范大学,2012,7(3). |
APA | Yuan, Menglong.,Chen, Ming.,Zhang, Wei.,Lu, Wei.,Wang, Jin.,...&Lin, Min.(2012).Genome Sequence and Transcriptome Analysis of the Radioresistant Bacterium Deinococcus gobiensis. Insights into the Extreme Environmental Adaptations.PLOS ONE,7(3). |
MLA | Yuan, Menglong,et al."Genome Sequence and Transcriptome Analysis of the Radioresistant Bacterium Deinococcus gobiensis. Insights into the Extreme Environmental Adaptations".PLOS ONE 7.3(2012). |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。