Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1242/jeb.054403 |
Aestivation: signaling and hypometabolism | |
Storey, Kenneth B.; Storey, Janet M. | |
通讯作者 | Storey, Kenneth B. |
来源期刊 | JOURNAL OF EXPERIMENTAL BIOLOGY
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ISSN | 0022-0949 |
出版年 | 2012 |
卷号 | 215期号:9页码:1425-1433 |
英文摘要 | Aestivation is a survival strategy used by many vertebrates and invertebrates to endure arid environmental conditions. Key features of aestivation include strong metabolic rate suppression, strategies to retain body water, conservation of energy and body fuel reserves, altered nitrogen metabolism, and mechanisms to preserve and stabilize organs, cells and macromolecules over many weeks or months of dormancy. Cell signaling is crucial to achieving both a hypometabolic state and reorganizing multiple metabolic pathways to optimize long-term viability during aestivation. This commentary examines the current knowledge about cell signaling pathways that participate in regulating aestivation, including signaling cascades mediated by the AMP-activated kinase, Akt, ERK, and FoxO1. |
英文关键词 | antioxidant defense metabolic rate depression regulation of gene expression reversible protein phosphorylation signal transduction pathway signaling cascade |
类型 | Article |
语种 | 英语 |
国家 | Canada |
收录类别 | SCI-E |
WOS记录号 | WOS:000302786300009 |
WOS关键词 | METABOLIC-RATE DEPRESSION ; ACTIVATED PROTEIN-KINASE ; AFRICAN CLAWED FROG ; SNAIL OTALA-LACTEA ; ALBOGUTTATA GUNTHER 1867 ; LAND SNAIL ; XENOPUS-LAEVIS ; CYCLORANA-ALBOGUTTATA ; ANTIOXIDANT DEFENSES ; DEHYDRATION STRESS |
WOS类目 | Biology |
WOS研究方向 | Life Sciences & Biomedicine - Other Topics |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/173503 |
作者单位 | Carleton Univ, Inst Biochem, Ottawa, ON K1S 5B6, Canada |
推荐引用方式 GB/T 7714 | Storey, Kenneth B.,Storey, Janet M.. Aestivation: signaling and hypometabolism[J],2012,215(9):1425-1433. |
APA | Storey, Kenneth B.,&Storey, Janet M..(2012).Aestivation: signaling and hypometabolism.JOURNAL OF EXPERIMENTAL BIOLOGY,215(9),1425-1433. |
MLA | Storey, Kenneth B.,et al."Aestivation: signaling and hypometabolism".JOURNAL OF EXPERIMENTAL BIOLOGY 215.9(2012):1425-1433. |
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