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In the arid and semi-arid northeastern Brazil, the cultivation of cowpea has stood out for being an adaptable culture conditions in the region. Because of the ability of cowpea, in symbiosis with rhizobia carry out the FBN, the co-inoculation Rhizobium and growth promoting bacteria in plants can optimize the fixation of atmospheric N2 depending on the combination and compatibility of the strains involved. The objective of this study was to evaluate the response of the inoculation BPCP’s and Bradyrhizobium sp. as an alternative to optimize performance and development of symbiotic cowpea under conditions of green-house. The experiment was conducted in a greenhouse, using as substrate washed and sterilized sand in Leonard jars. The treatments were: 22 strains BPCP’s compared with the strain (BR 3267), on cowpea cv. IPA 206. At harvest 35 days after planting (DAP) and the following variables were evaluated: plant height (AP) 15, 25 and 35 days, root length (CR), shoot dry matter (MSPA), root dry matter (MSR), nodule dry matter (MSN), specific nodulation (NE) and nitrogen accumulated in shoots (Nac). The results show that the culture of cowpea responded significantly to inoculation of strains of Bacillus, Brevibacillus and Paenibacillus co-inoculated with the strain of Bradyrhizobium sp. (BR 3267). The interaction of microorganisms studied non-influenced the variables specific nodulation and dry matter of nodules in cowpea cv. IPA 206. The strain of Paenibacillus graminis (MC 04/21) co-inoculated with Bradyrhizobium sp. (BR 3267) was higher compared to other strains tested in the production of nitrogen accumulated in shoot dry matter, providing a better performance symbiotic.