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We present a new U-series dated speleothem record (PC-1) from the Great Basin that documents deglacial climate variability between ca 20.1 and 15.6 ka. Our data show an abrupt 18.6 ka cold event preceding Heinrich event 1 that is consistent with expansion of the Laurentide Ice sheet during the ’binge’ phase of ice growth. This event coincided with dessication of pluvial Lake Mojave suggesting cold and dry conditions in the southern Great Basin at this time. PC-1 delta O-18 values before and during Heinrich event 1 are similar, but an increase in stalagmite growth rates suggests wetter conditions that coincided with deposition of spring deposits in southern Nevada. The time interval of our record is consistent with the timing of pluvial conditions in the Great Basin as evident from a comparison to regional wetness proxies. Our new speleothem record, recovered from the recharge area for Devils Hole, does not show a delta O-18 increase coincident with the abrupt increase in Devils Hole delta O-18 at c. 18 ka, challenging the view that the Great Basin experienced an early Termination I. This hypothesis is supported by two other southwest speleothem records that demonstrate deglaciation was synchronous with forcing from the North Atlantic Ocean. We suggest that Devils Hole speleothem delta O-18 values may partly reflect source water changes in the regional aquifer. Further, Devils Hole delta C-13 minima coincide with peak global glacial conditions and weak Asian monsoon periods, suggesting that they constrain better the timing of pluvial conditions in the Great Basin. (C) 2011 Elsevier Ltd. All rights reserved.