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In this study, the changes in desert boundaries in Asia (Gobi, Karakum, Lut, Taklimakan, and Thar deserts) during the growing season (April-October) in the years 1982-2008 were investigated by analyzing the normalized difference vegetation index (NDVI), precipitation, and temperature. In the desert boundary regions, the domain mean NDVI values increased by 7.2% per decade in 1982-1998 but decreased by 6.8% per decade thereafter. Accordingly, the bare soil areas (or nonvegetated areas) of the inside of the desert boundaries contracted by 9.8% per decade in the 1990s and expanded by 8.7% per decade in the 2000s. It is noted that the five deserts experience nearly simultaneous NDVI changes although they cover a very diverse area of Asia. In contrast, changes in temperature and precipitation in the deserts show rather diverse results. In desert boundaries located along 40 degrees N (Gobi, Taklimakan, and Karakum), the decadal changes in vegetation greenness were mainly related to regional climate during the entire analysis period. Precipitation increased in the 1990s, providing favorable conditions for vegetation growth (i.e., greening), but precipitation reduced (19 mm per decade) and warming intensified (0.7 degrees C per decade) in the 2000s, causing less moisture to be available for vegetation growth (i.e., browning). In desert boundaries below 40 degrees N (Lut and Thar), although an increase in precipitation (8 mm per decade) led to greening in the 1990s, local changes in precipitation and temperature did not necessarily cause browning in the 2000s. Observed multidecadal changes in vegetation greenness in the present study suggest that under significant global and/or regional warming, changes in moisture availability for vegetation growth in desert boundaries are an important factor when understanding decadal changes in areas vulnerable to desertification over Asia.