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Amphibolite-grade quartzofeldspathic gneiss domes surrounded by greenschist-grade island arc and ophiolitic assemblages is a characteristic feature of the Arabian-Nubian Shield in the Eastern Desert of Egypt. The mode of formation of these domes, including the Meatiq Gneiss Dome, is controversial, as is the protolith age of these gneisses. Reinvestigation of selected segments of the Eastern Desert Shear Zone (EDSZ), a high-strain zone separating the eugeoclinal units from the underlying quartzofeldspathic gneisses show it to be a top-to-the NW shear zone which was later folded about a NW-SE trending fold axis (long axis of the gneiss dome). Kinematic indicators (shear bands, duplex structures, etc.) along the north-eastern and south-western flanks of the dome therefore show apparent left-lateral and right-lateral strike-slip displacement across the EDSZ. These observations are in conflict with most previous tectonic models which link formation of the dome to extension in a NW-SE oriented corridor bordered by two sub-parallel left-lateral NW-SE oriented strike-slip faults. Emplacement of upper crustal, low-grade, eugeoclinal rocks tectonically on top of middle crustal amphibolite-grade quartzofeldspathic gneisses indicates that the EDSZ may represents an extensional fault with a possible break-away zone in the southern part of the Eastern Desert. Alternatively it can be explained as the result of two (or more) tectonometamorphic events with an intervening episode of erosion and exhumation of high grade rocks prior to emplacement of the eugeoclinal thrust complex. Recent U-Pb TIMS ages on syntectonic orthogneisses and post-tectonic granites in the area show that shearing and subsequent doming must be younger than 630 Ma, possibly as young as 600 Ma. (C) 2009 Elsevier Ltd. All rights reserved.