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Early to late Pleistocene Be-10 exposure ages of abandoned surfaces in the Negev desert reveal the regional drainage evolution history and its relationship with the subsidence of the western margin of the Dead Sea Rift. The dated desert paved surfaces have developed over originally westward-flowing rivers which were, abandoned by early Pleistocene and whose relicts are now progressively tilted towards the rift axis. The slow and non-destructive subsidence coupled with extreme hyperaridity enabled the preservation of these ancient surfaces along some of the main water divides in the Negev, nearly irrespective of their distance from the rift axis. Constraints on the tilting history are obtained from analyzing the spatial pattern of the exposure ages, suggesting subsidence rates as low as 120-300 m Ma(-1) in the southern Arava Valley since the late Pliocene. It is shown that the transition from the Pliocene to current drainage pattern occurred over a short period during the early Pleistocene, and that the governing fluvial response that followed the delineation of current basins is represented by a continuous spectrum of ages of inset terraces. (C) 2009 Elsevier B.V. All rights reserved.