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DOI | 10.1016/j.berh.2010.05.006 |
Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis | |
Chandran, Vinod1; Rahman, Proton2 | |
通讯作者 | Rahman, Proton |
来源期刊 | BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
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ISSN | 1521-6942 |
EISSN | 1521-1770 |
出版年 | 2010 |
卷号 | 24期号:5页码:579-588 |
英文摘要 | Spondyloarthritis refers to a group of inflammatory rheumatic diseases that share common clinical and genetic characteristics Due to the rapid advances in technology and computational genetics there is now an increasing list of well-validated genes in spondyloarthritis The newest genetic associations are of modest magnitude and have been identified as a result of analysing thousands of samples using genome-wide association scans or targeted candidate-gene association studies In this article we will highlight the genes associated with spondyloarthruis with an emphasis on the recent candidate genes that have been identified in ankylosing spondylitis and psoriatic arthritis If applicable we will also discuss their potential relevance to the clinical rheumatologist (C) 2010 Elsevier Ltd All rights reserved |
英文关键词 | Psoriasis Major histocompatibility complex Human leukocyte antigen genes Genetic linkage Genetic association Endoplasmic reticulum (ER) associated aminopeptidase 1 Interleukin 23 receptor Gene deserts |
类型 | Article |
语种 | 英语 |
国家 | Canada |
收录类别 | SCI-E |
WOS记录号 | WOS:000284674600002 |
WOS关键词 | INFANTILE SYSTEMIC HYALINOSIS ; GENOME-WIDE ASSOCIATION ; RHEUMATOID-ARTHRITIS ; CANADIAN POPULATIONS ; SUSCEPTIBILITY LOCI ; MICA RATHER ; TNF-ALPHA ; HLA-C ; DISEASE ; POLYMORPHISMS |
WOS类目 | Rheumatology |
WOS研究方向 | Rheumatology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/163434 |
作者单位 | 1.Univ Toronto, Dept Med, Div Rheumatol, Toronto, ON, Canada; 2.Mem Univ Newfoundland, St John, NF, Canada |
推荐引用方式 GB/T 7714 | Chandran, Vinod,Rahman, Proton. Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis[J],2010,24(5):579-588. |
APA | Chandran, Vinod,&Rahman, Proton.(2010).Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis.BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY,24(5),579-588. |
MLA | Chandran, Vinod,et al."Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis".BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY 24.5(2010):579-588. |
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