Arid
DOI10.1016/j.berh.2010.05.006
Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis
Chandran, Vinod1; Rahman, Proton2
通讯作者Rahman, Proton
来源期刊BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
ISSN1521-6942
EISSN1521-1770
出版年2010
卷号24期号:5页码:579-588
英文摘要

Spondyloarthritis refers to a group of inflammatory rheumatic diseases that share common clinical and genetic characteristics Due to the rapid advances in technology and computational genetics there is now an increasing list of well-validated genes in spondyloarthritis The newest genetic associations are of modest magnitude and have been identified as a result of analysing thousands of samples using genome-wide association scans or targeted candidate-gene association studies In this article we will highlight the genes associated with spondyloarthruis with an emphasis on the recent candidate genes that have been identified in ankylosing spondylitis and psoriatic arthritis If applicable we will also discuss their potential relevance to the clinical rheumatologist (C) 2010 Elsevier Ltd All rights reserved


英文关键词Psoriasis Major histocompatibility complex Human leukocyte antigen genes Genetic linkage Genetic association Endoplasmic reticulum (ER) associated aminopeptidase 1 Interleukin 23 receptor Gene deserts
类型Article
语种英语
国家Canada
收录类别SCI-E
WOS记录号WOS:000284674600002
WOS关键词INFANTILE SYSTEMIC HYALINOSIS ; GENOME-WIDE ASSOCIATION ; RHEUMATOID-ARTHRITIS ; CANADIAN POPULATIONS ; SUSCEPTIBILITY LOCI ; MICA RATHER ; TNF-ALPHA ; HLA-C ; DISEASE ; POLYMORPHISMS
WOS类目Rheumatology
WOS研究方向Rheumatology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/163434
作者单位1.Univ Toronto, Dept Med, Div Rheumatol, Toronto, ON, Canada;
2.Mem Univ Newfoundland, St John, NF, Canada
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GB/T 7714
Chandran, Vinod,Rahman, Proton. Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis[J],2010,24(5):579-588.
APA Chandran, Vinod,&Rahman, Proton.(2010).Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis.BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY,24(5),579-588.
MLA Chandran, Vinod,et al."Update on the genetics of spondyloarthritis - ankylosing spondylitis and psoriatic arthritis".BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY 24.5(2010):579-588.
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