Arid
DOI10.1097/01.ASW.0000363485.17224.26
Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology
Romanelli, Marco; Dini, Valentina; Bertone, Maria Stefania
通讯作者Romanelli, Marco
来源期刊ADVANCES IN SKIN & WOUND CARE
ISSN1527-7941
出版年2010
卷号23期号:1页码:34-38
英文摘要

OBJECTIVE: In this study, a biological extracellular matrix was compared with a moist wound dressing to determine its effectiveness in the treatment of mixed arterial/venous and venous ulcers.


METHODS: Patients were evaluated for complete wound healing, time to dressing change, and formation of granulation tissue.


RESULTS: Extracellular matrix-treated ulcers achieved complete healing on average in 5.4 weeks as compared with 8.3 weeks for the control group treated with moist wound dressing (P = .02). At the primary time point evaluated (8 weeks), complete wound closure was achieved in 80% of extracellular matrix-treated ulcers compared with 65% of ulcers in the control group (P < .05). Statistically significant differences favoring the extracellular-matrix treatment group were also reported for time to dressing change (P < .05), and for percentage of granulation tissue formed (P < .05).


CONCLUSION: Overall, the biological extracellular matrix was more beneficial than moist wound dressings for the treatment of patients with mixed arterial/venous or venous ulcers. ADV SKIN WOUND CARE 2010;23:34-8


类型Article
语种英语
国家Italy
收录类别SCI-E ; SSCI
WOS记录号WOS:000295842200009
WOS关键词SMALL-INTESTINAL SUBMUCOSA ; DIABETIC FOOT ULCERS ; CHRONIC LEG ULCERS ; EXTRACELLULAR-MATRIX ; GROWTH-FACTOR ; TRIAL ; FIBROBLASTS ; MANAGEMENT ; FLUID ; GRAFT
WOS类目Dermatology ; Nursing ; Surgery
WOS研究方向Dermatology ; Nursing ; Surgery
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/162955
作者单位Univ Pisa, Wound Healing Res Unit, Dept Dermatol, I-56100 Pisa, Italy
推荐引用方式
GB/T 7714
Romanelli, Marco,Dini, Valentina,Bertone, Maria Stefania. Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology[J],2010,23(1):34-38.
APA Romanelli, Marco,Dini, Valentina,&Bertone, Maria Stefania.(2010).Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology.ADVANCES IN SKIN & WOUND CARE,23(1),34-38.
MLA Romanelli, Marco,et al."Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology".ADVANCES IN SKIN & WOUND CARE 23.1(2010):34-38.
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