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DOI | 10.1097/01.ASW.0000363485.17224.26 |
Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology | |
Romanelli, Marco; Dini, Valentina; Bertone, Maria Stefania | |
通讯作者 | Romanelli, Marco |
来源期刊 | ADVANCES IN SKIN & WOUND CARE
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ISSN | 1527-7941 |
出版年 | 2010 |
卷号 | 23期号:1页码:34-38 |
英文摘要 | OBJECTIVE: In this study, a biological extracellular matrix was compared with a moist wound dressing to determine its effectiveness in the treatment of mixed arterial/venous and venous ulcers. METHODS: Patients were evaluated for complete wound healing, time to dressing change, and formation of granulation tissue. RESULTS: Extracellular matrix-treated ulcers achieved complete healing on average in 5.4 weeks as compared with 8.3 weeks for the control group treated with moist wound dressing (P = .02). At the primary time point evaluated (8 weeks), complete wound closure was achieved in 80% of extracellular matrix-treated ulcers compared with 65% of ulcers in the control group (P < .05). Statistically significant differences favoring the extracellular-matrix treatment group were also reported for time to dressing change (P < .05), and for percentage of granulation tissue formed (P < .05). CONCLUSION: Overall, the biological extracellular matrix was more beneficial than moist wound dressings for the treatment of patients with mixed arterial/venous or venous ulcers. ADV SKIN WOUND CARE 2010;23:34-8 |
类型 | Article |
语种 | 英语 |
国家 | Italy |
收录类别 | SCI-E ; SSCI |
WOS记录号 | WOS:000295842200009 |
WOS关键词 | SMALL-INTESTINAL SUBMUCOSA ; DIABETIC FOOT ULCERS ; CHRONIC LEG ULCERS ; EXTRACELLULAR-MATRIX ; GROWTH-FACTOR ; TRIAL ; FIBROBLASTS ; MANAGEMENT ; FLUID ; GRAFT |
WOS类目 | Dermatology ; Nursing ; Surgery |
WOS研究方向 | Dermatology ; Nursing ; Surgery |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/162955 |
作者单位 | Univ Pisa, Wound Healing Res Unit, Dept Dermatol, I-56100 Pisa, Italy |
推荐引用方式 GB/T 7714 | Romanelli, Marco,Dini, Valentina,Bertone, Maria Stefania. Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology[J],2010,23(1):34-38. |
APA | Romanelli, Marco,Dini, Valentina,&Bertone, Maria Stefania.(2010).Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology.ADVANCES IN SKIN & WOUND CARE,23(1),34-38. |
MLA | Romanelli, Marco,et al."Randomized Comparison of OASIS Wound Matrix versus Moist Wound Dressing in the Treatment of Difficult-to-Heal Wounds of Mixed Arterial/Venous Etiology".ADVANCES IN SKIN & WOUND CARE 23.1(2010):34-38. |
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