Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1111/j.1348-0421.2009.00183.x |
A new antimicrobial peptide isolated from Oudneya africana seeds | |
Hammami, Riadh2,3; Ben Hamida, Jeannette2; Vergoten, Gerard3; Lacroix, Jean-Marie3; Slomianny, Marie-Christine3; Mohamed, Neffati4; Fliss, Ismail1 | |
通讯作者 | Fliss, Ismail |
来源期刊 | MICROBIOLOGY AND IMMUNOLOGY
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ISSN | 0385-5600 |
EISSN | 1348-0421 |
出版年 | 2009 |
卷号 | 53期号:12页码:658-666 |
英文摘要 | Oudneya africana R. Br. (Brassicaceae), a wild-growing plant in the arid region of Tunisia, is used in ethno-medicinal treatment of microbial infections. Validation of ethno-therapeutic claims pertaining to the plant was sought by investigating its antimicrobial activity. A proteinaceous extract of the seeds, called AS-3000, showed activity against various organisms including L. monocytogenes, E. coli, B. subtilis, E. hirae, P. aeruginosa, S. aureus and C. albicans. Extract AS-3000 exhibited a synergistic effect against L. ivanovii when combined with vancomycin or chloramphenicol. The post-antibiotic inhibitory effect of the ampicillin/AS-3000 combination was 2.3-fold greater than for the antibiotic alone. The mode of action of AS-3000 on Listeria and Escherichia was visible using SEM. These results support the use of O. africana for treating microbial infections. |
英文关键词 | antimicrobial peptide Oudneya africana plant extract synergism |
类型 | Article |
语种 | 英语 |
国家 | Canada ; Tunisia ; France |
收录类别 | SCI-E |
WOS记录号 | WOS:000272306700002 |
WOS关键词 | MEDICINAL-PLANTS ; DEFENSINS ; IMMUNITY |
WOS类目 | Immunology ; Microbiology |
WOS研究方向 | Immunology ; Microbiology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/161943 |
作者单位 | 1.Univ Laval, Dept Aliments & Nutr, Inst Nutr & Funct Food INAF, Quebec City, PQ G1K 7P4, Canada; 2.Univ Tunis El Manar, Unity Funct Prote & Food Biopreservat, Higher Inst Appl Biol Sci Tunis, Tunis, Tunisia; 3.Univ Sci & Technol Lille, Dept Struct & Funct Glycobiol, CNRS, UMR 8576, Lille, France; 4.Natl Inst Arid Areas, Lab Pastoral Ecol, Medenine, Tunisia |
推荐引用方式 GB/T 7714 | Hammami, Riadh,Ben Hamida, Jeannette,Vergoten, Gerard,et al. A new antimicrobial peptide isolated from Oudneya africana seeds[J],2009,53(12):658-666. |
APA | Hammami, Riadh.,Ben Hamida, Jeannette.,Vergoten, Gerard.,Lacroix, Jean-Marie.,Slomianny, Marie-Christine.,...&Fliss, Ismail.(2009).A new antimicrobial peptide isolated from Oudneya africana seeds.MICROBIOLOGY AND IMMUNOLOGY,53(12),658-666. |
MLA | Hammami, Riadh,et al."A new antimicrobial peptide isolated from Oudneya africana seeds".MICROBIOLOGY AND IMMUNOLOGY 53.12(2009):658-666. |
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