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This study was carried out to evaluate the effects of compost application produced from municipal solid wastes on growth and yield of wheat under semi-arid Mediterranean conditions. The compost was produced from mainly house-originated solid wastes, bay leaves and farmyard manure mixture in a ratio of 7.5:1.5:1.0, respectively. The treatments were: chemical fertilizer (160 kg N ha(-1) and 80 kg P(2)O(5) ha(-1)); 20, 40, 60 and 80 tons compost ha(-1); 80 tons animal manure ha(-1) and control without treatments. The experimental design was randomized blocks with three replications. According to the results of a three-year experiment, application of 20 tons of compost ha(-1) appeared to be the most suitable treatment for satisfied yield. Moreover, some positive effects of the compost application on growth parameters of wheat were observed.