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A glacier-climate model was used to calculate climatic conditions in a test site on the east Andean slope around Cochabamba (17 degrees S, Bolivia) for the time of the maximum Late Pleistocene glaciation. Results suggest a massive temperature reduction of about -6.4 degrees C (+ 1.4/-1.3 degrees C), combined with annual precipitation rates of about 1100 mm (+570 mm/-280 mm). This implies no major change in annual precipitation compared with today. Summer precipitation was the source for the humidity in the past, as is the case today. This climate scenario argues for a maximum advance of the paleo-glaciers in the eastern cordillera during the global Last Glacial Maximum (LGM, 20 ka BP), which is confirmed by exposure age dates. In a synthesized view over the central Andes, the results point to an increased summer precipitation-driven Late Glacial (15-10 ka BP) maximum advance in the western part of the Altiplano (18 degrees S-23 degrees S), a temperature-driven maximum advance during full glacial times (LGM) in the eastern cordillera, and a pre- and post-LGM (32 ka BP/14 ka BP) maximum advance around 30 S related to increased precipitation and reduced temperature on the western slope of the Andes. The results indicate the importance of understanding the seasonality and details of the mass balance-climate interaction in order to disentangle drivers for the observed regionally asynchronous past glaciations in the central Andes. (c) 2007 Elsevier B.V. All rights reserved.