Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.1186/1471-2458-8-78 |
Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples | |
Ferreccio, Catterina1; Corvalan, Alejandro1; Margozzini, Paula1; Viviani, Paola1; Gonzalez, Claudia2; Aguilera, Ximena2; Gravitt, Patti E.3 | |
通讯作者 | Ferreccio, Catterina |
来源期刊 | BMC PUBLIC HEALTH |
ISSN | 1471-2458 |
出版年 | 2008 |
卷号 | 8 |
英文摘要 | Background: Chile has broad variations in weather, economics and population from the far desert north (Region 1) to the cold, icy south (Region 12). A home-based self-collected vaginal sampling was nested in the 2003 Chilean population-based health survey in order to explore the possibility of a type-specific geographical variation for human papillomavirus Methods: The population was a national probability sample of people 17 years of age and over. Consenting women provided self-collected cervicovaginal swabs in universal collection media (UCM). DNA was extracted and typed to 37 HPV genotypes using PGMY consensus PCR and line blot assay. Weighted prevalence rates and adjusted OR were calculated. Results: Of the 1,883 women participating in the health survey, 1,219 (64.7%) provided a cervicovaginal sample and in 1,110 (56.2% of participants and 66.5% of those eligible) the samples were adequate for analysis. Refusal rate was 16.9%. HPV prevalence was 29.2% (15.1% high-risk HPV and 14.1% low-risk HPV). Predominant high-risk types were HPV 16, 52, 51, 56 and 58. Predominant low-risk HPVs were HPV 84, CP6108, 62, 53 and 61. High-risk and low-risk HPV rates were inversely correlated between the regions. High-risk HPV prevalence was highest among the youngest women, whereas low-risk HPV increased slightly with age. Conclusion: Self-obtained vaginal sampling is adequate for monitoring HPV in the community, for identifying high-risk areas, and for surveying the long term impact of interventions. |
类型 | Article |
语种 | 英语 |
国家 | Chile ; USA |
收录类别 | SCI-E |
WOS记录号 | WOS:000255175000001 |
WOS关键词 | HUMAN-PAPILLOMAVIRUS INFECTION ; CERVICAL NEOPLASIA ; UNITED-STATES ; COSTA-RICA ; RISK TYPES ; WOMEN ; AGE ; DNA ; POPULATION ; ADOLESCENT |
WOS类目 | Public, Environmental & Occupational Health |
WOS研究方向 | Public, Environmental & Occupational Health |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/156722 |
作者单位 | 1.Pontificia Univ Catolica Chile, Escuela Med, Santiago, Chile; 2.Minist Salud, Dept Epidemiol, Santiago, Chile; 3.Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Baltimore, MD USA |
推荐引用方式 GB/T 7714 | Ferreccio, Catterina,Corvalan, Alejandro,Margozzini, Paula,et al. Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples[J],2008,8. |
APA | Ferreccio, Catterina.,Corvalan, Alejandro.,Margozzini, Paula.,Viviani, Paola.,Gonzalez, Claudia.,...&Gravitt, Patti E..(2008).Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples.BMC PUBLIC HEALTH,8. |
MLA | Ferreccio, Catterina,et al."Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples".BMC PUBLIC HEALTH 8(2008). |
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