Arid
DOI10.1186/1471-2458-8-78
Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples
Ferreccio, Catterina1; Corvalan, Alejandro1; Margozzini, Paula1; Viviani, Paola1; Gonzalez, Claudia2; Aguilera, Ximena2; Gravitt, Patti E.3
通讯作者Ferreccio, Catterina
来源期刊BMC PUBLIC HEALTH
ISSN1471-2458
出版年2008
卷号8
英文摘要

Background: Chile has broad variations in weather, economics and population from the far desert north (Region 1) to the cold, icy south (Region 12). A home-based self-collected vaginal sampling was nested in the 2003 Chilean population-based health survey in order to explore the possibility of a type-specific geographical variation for human papillomavirus


Methods: The population was a national probability sample of people 17 years of age and over. Consenting women provided self-collected cervicovaginal swabs in universal collection media (UCM). DNA was extracted and typed to 37 HPV genotypes using PGMY consensus PCR and line blot assay. Weighted prevalence rates and adjusted OR were calculated.


Results: Of the 1,883 women participating in the health survey, 1,219 (64.7%) provided a cervicovaginal sample and in 1,110 (56.2% of participants and 66.5% of those eligible) the samples were adequate for analysis. Refusal rate was 16.9%. HPV prevalence was 29.2% (15.1% high-risk HPV and 14.1% low-risk HPV). Predominant high-risk types were HPV 16, 52, 51, 56 and 58. Predominant low-risk HPVs were HPV 84, CP6108, 62, 53 and 61. High-risk and low-risk HPV rates were inversely correlated between the regions. High-risk HPV prevalence was highest among the youngest women, whereas low-risk HPV increased slightly with age.


Conclusion: Self-obtained vaginal sampling is adequate for monitoring HPV in the community, for identifying high-risk areas, and for surveying the long term impact of interventions.


类型Article
语种英语
国家Chile ; USA
收录类别SCI-E
WOS记录号WOS:000255175000001
WOS关键词HUMAN-PAPILLOMAVIRUS INFECTION ; CERVICAL NEOPLASIA ; UNITED-STATES ; COSTA-RICA ; RISK TYPES ; WOMEN ; AGE ; DNA ; POPULATION ; ADOLESCENT
WOS类目Public, Environmental & Occupational Health
WOS研究方向Public, Environmental & Occupational Health
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/156722
作者单位1.Pontificia Univ Catolica Chile, Escuela Med, Santiago, Chile;
2.Minist Salud, Dept Epidemiol, Santiago, Chile;
3.Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Baltimore, MD USA
推荐引用方式
GB/T 7714
Ferreccio, Catterina,Corvalan, Alejandro,Margozzini, Paula,et al. Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples[J],2008,8.
APA Ferreccio, Catterina.,Corvalan, Alejandro.,Margozzini, Paula.,Viviani, Paola.,Gonzalez, Claudia.,...&Gravitt, Patti E..(2008).Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples.BMC PUBLIC HEALTH,8.
MLA Ferreccio, Catterina,et al."Baseline assessment of prevalence and geographical distribution of HPV types in Chile using self-collected vaginal samples".BMC PUBLIC HEALTH 8(2008).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Ferreccio, Catterina]的文章
[Corvalan, Alejandro]的文章
[Margozzini, Paula]的文章
百度学术
百度学术中相似的文章
[Ferreccio, Catterina]的文章
[Corvalan, Alejandro]的文章
[Margozzini, Paula]的文章
必应学术
必应学术中相似的文章
[Ferreccio, Catterina]的文章
[Corvalan, Alejandro]的文章
[Margozzini, Paula]的文章
相关权益政策
暂无数据
收藏/分享

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。