干旱区生态环境知识资源中心(Arid): Mass fingerprinting of toxic fractions from the venom of the Indian red scorpion, Mesobuthus tamulus: Biotope-specific variation in the expression of venom peptides

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DOI	10.1002/rcm.3240
	Mass fingerprinting of toxic fractions from the venom of the Indian red scorpion, Mesobuthus tamulus: Biotope-specific variation in the expression of venom peptides
	Newton, Kirsti A.; Clench, Malcolm R.; Deshmukh, Ranjana; Jeyaseelan, Kandiah; Strong, Peter N.
通讯作者	Newton, Kirsti A.
来源期刊	RAPID COMMUNICATIONS IN MASS SPECTROMETRY
ISSN	0951-4198
EISSN	1097-0231
出版年	2007
卷号	21 期号:21 页码:3467-3476
英文摘要	The red scorpion, Mesobuthus tamulus, is found in two distinct biotopes within the Indian state of Maharastra - a tropical, sea-level biotope and a semi-arid biotope, up to 600 m. Scorpions from these two geographical areas show marked differences in toxicity. Using mass spectrometry, we have shown biotope-specific variation in the expression of peptides from scorpions collected from these two distinct areas. Matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOFMS) and reversed-phase liquid chromatography/electrospray ionisation mass spectrometry (LC/ESI-MS) were assessed as techniques for obtaining mass fingerprint data. On line LC/ESI-MS was judged to be the method of choice and unique biotope-specific mass fingerprints, with key diagnostic markers, were obtained. Copyright (C) 2007 John Wiley & Sons, Ltd.
类型	Article
语种	英语
国家	England ; India ; Singapore
收录类别	SCI-E
WOS记录号	WOS:000250608300009
WOS关键词	TIME-OF-FLIGHT ; PERFORMANCE LIQUID-CHROMATOGRAPHY ; TITYUS-SERRULATUS SCORPIONES ; INTRASPECIFIC VARIATION ; PROTEOMIC ANALYSIS ; POTASSIUM CHANNEL ; MOVING PIECES ; K+-CHANNELS ; SPECTROMETRY ; VARIABILITY
WOS类目	Biochemical Research Methods ; Chemistry, Analytical ; Spectroscopy
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry ; Spectroscopy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/155858
作者单位	(1)Sheffield Hallam Univ, Biosci Div, Sheffield S1 1WB, S Yorkshire, England;(2)Haffkine Inst, Bombay 400012, Maharashtra, India;(3)Natl Univ Singapore, Dept Biochem, Singapore 117597, Singapore
推荐引用方式 GB/T 7714	Newton, Kirsti A.,Clench, Malcolm R.,Deshmukh, Ranjana,et al. Mass fingerprinting of toxic fractions from the venom of the Indian red scorpion, Mesobuthus tamulus: Biotope-specific variation in the expression of venom peptides[J],2007,21(21):3467-3476.
APA	Newton, Kirsti A.,Clench, Malcolm R.,Deshmukh, Ranjana,Jeyaseelan, Kandiah,&Strong, Peter N..(2007).Mass fingerprinting of toxic fractions from the venom of the Indian red scorpion, Mesobuthus tamulus: Biotope-specific variation in the expression of venom peptides.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,21(21),3467-3476.
MLA	Newton, Kirsti A.,et al."Mass fingerprinting of toxic fractions from the venom of the Indian red scorpion, Mesobuthus tamulus: Biotope-specific variation in the expression of venom peptides".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 21.21(2007):3467-3476.