干旱区生态环境知识资源中心(Arid): Development of a frit-free SPE-based in-column preconcentration system for capillary electrophoresis

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DOI	10.1016/j.jpba.2006.12.031
	Development of a frit-free SPE-based in-column preconcentration system for capillary electrophoresis
	Saavedra, L.; Maeso, N.; Cifuentes, A.; Barbas, C.
通讯作者	Barbas, C.
来源期刊	JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
ISSN	0731-7085
出版年	2007
卷号	44 期号:2 页码:471-476
英文摘要	An in-capillary sample preconcentration strategy based on solid phase extraction (SPE) technology coupled with capillary electrophoresis (CE) has been developed taking advantage of both techniques (SPE and CE). An in-line frit-free preconcentration device for capillary electrophoresis containing MCX beads. obtained from the corresponding Waters OASIS (R) cartridges, was prepared. The retention of the particles was based on the relative diameters of the particles, carefully selected, and the capillaries. An experimental preconcentration factor of 100 was found for the system. Conditions were optimised for 3-nitrotyrosine measurement in rat urine being 4.4 mu M spiked in the urine the lowest value detectable. (c) 2007 Elsevier B.V. All rights reserved.
英文关键词	solid phase extraction sample preconcentration cleanup small molecules capillary electrophoresis
类型	Article
语种	英语
国家	Spain
收录类别	SCI-E
WOS记录号	WOS:000247765400019
WOS关键词	VOLUME SAMPLE STACKING ; MASS-SPECTROMETRY ; ONLINE PRECONCENTRATION ; TRACE ANALYSIS ; URINE ; 3-NITROTYROSINE ; NITROTYROSINE ; SEPARATION
WOS类目	Chemistry, Analytical ; Pharmacology & Pharmacy
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/155210
作者单位	(1)Univ San Pablo, Fac Farm, Secc Quim Analit, Madrid 28668, Spain;(2)CSIC, Inst Fermentac Ind, E-28006 Madrid, Spain
推荐引用方式 GB/T 7714	Saavedra, L.,Maeso, N.,Cifuentes, A.,et al. Development of a frit-free SPE-based in-column preconcentration system for capillary electrophoresis[J],2007,44(2):471-476.
APA	Saavedra, L.,Maeso, N.,Cifuentes, A.,&Barbas, C..(2007).Development of a frit-free SPE-based in-column preconcentration system for capillary electrophoresis.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,44(2),471-476.
MLA	Saavedra, L.,et al."Development of a frit-free SPE-based in-column preconcentration system for capillary electrophoresis".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 44.2(2007):471-476.