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DOI10.1016/j.phytochem.2006.06.030
Chemistry and biological activity of secondary metabolites in Euphorbia from Iran
Jassbi, Amir Reza
通讯作者Jassbi, Amir Reza
来源期刊PHYTOCHEMISTRY
ISSN0031-9422
出版年2006
卷号67期号:18页码:1977-1984
英文摘要

The chemical constituents of some species of Euphorbia, which grow mostly in semi-desert areas in Iran and on the Alborz Mountains in the north of Tehran, have been found to include chemotaxonomically important myrsinane diterpenoids and cycloartane triterpenoids. The Euphorbia plants collected in province of Azarbaijan in the northwestern part of Iran contained mostly derivatives of skin-irritating ingenol esters. Some of the diterpenoids with myrsinane carbon skeleton inhibited enzymes such as alpha-glycosidase, urease, HIV-1 reverse transcriptase, and prolyl endopeptidase. They also showed analgesic and DNA-damaging activities. The present review describes the chemistry and biological activity of several compounds isolated from different species of Iranian Euphorbia: diterpenoids with myrsinane skeletons, flavonoids, tannins, alkanes, sterols, mono-, sesqui- and triterpenoids, skin-irritating and tumor-promoting latexes and their active ingenol diterpenoids. (c) 2006 Elsevier Ltd. All rights reserved.


英文关键词Iranian Euphorbia myrsinane diterpenoids triterpenoids flavonoids skin irritant tumor promoter enzyme inhibitor
类型Review
语种英语
国家Germany ; Iran
收录类别SCI-E
WOS记录号WOS:000241205000002
WOS关键词SKIN IRRITANT ACTIVITY ; PENTACYCLIC DITERPENE ESTERS ; MOUSE LYMPHOMA-CELLS ; JATROPHANE DITERPENOIDS ; CHEMICAL-CONSTITUENTS ; MULTIDRUG-RESISTANCE ; SERRATA L ; L LATEX ; DECIPIENS ; INGENOL
WOS类目Biochemistry & Molecular Biology ; Plant Sciences
WOS研究方向Biochemistry & Molecular Biology ; Plant Sciences
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/152755
作者单位(1)Max Planck Inst Chem Ecol, Dept Mol Ecol, D-07745 Jena, Germany;(2)Shahid Beheshti Univ, Dept Phytochem, Med Plants Res Inst, Tehran, Iran
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GB/T 7714
Jassbi, Amir Reza. Chemistry and biological activity of secondary metabolites in Euphorbia from Iran[J],2006,67(18):1977-1984.
APA Jassbi, Amir Reza.(2006).Chemistry and biological activity of secondary metabolites in Euphorbia from Iran.PHYTOCHEMISTRY,67(18),1977-1984.
MLA Jassbi, Amir Reza."Chemistry and biological activity of secondary metabolites in Euphorbia from Iran".PHYTOCHEMISTRY 67.18(2006):1977-1984.
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