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Desert soil inorganic nutrients have their geological influence on wild medicinal herbs, plants and crop production. Soil samples collected from different areas of Cholistan desert were analysed for pH, moisture, soluble salts, organic contents, Na+, K+, Ca2+, Mg2+, Fe3+, Al3+, Cl-, CO32-, HCO3-, SO42- and PO43-. pH was observed from 7.30 to 8.85. Average level of nutrients were found higher in the order Al3+ (432.66+/- 205.93) > Fe3+ (289.54+/- 160.77) > SO42- (266.19+/- 215.59) > Cl- (247.08+/- 284.48) > HCO3- (78.45+/- 161.44) > CO32- (60.14+/- 41.26) > Ca2+ (53.16+/- 50.01) > Mg2+ (18.95+/- 19.39) > PO43- (18.72+/- 24.20) > Na+ (17.75+/- 15.34) K+ (15.81+/- 18.51). Data analysis for soluble salts and CO32- has showed negative skewness. Kurtosis data have shown random variations in results from positive to negative. Linear correlation coefficient matrix study has indicated strong positive correlation for certain pairs of nutrients.