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Droughts have been occurring persistently in southern African dryland regions for over a century. The impacts of droughts on people, their domesticated animals, wildlife, rangelands and cropped lands have been shown to be astronomical. If left alone the rangelands often recover after the calamity, however human occupation has led to irreversible damage. Even though some communities have evolved viable and sustainable coping mechanisms, recent times have seen weakened coping strategies leading to loss of life in most of the 10 countries in southern Africa. While land degradation has many inter-related causes and effects, drought-related effects have proven most difficult to manage and/or overcome. Drought-related land degradation or desertification poses a huge threat to sustainable land and resource management in the region. The paper examines appropriate drought mitigating initiatives, linking them to land tenure and land management practices. Numerous interventions targeted at reducing poverty and improvement in resource management have failed to achieve desired effects due to rigidity and imposition, and failure of the external interveners to recognise and incorporate indigenous peoples’ preferences and coping strategies. Non-governmental organisations and authorities’ willingness to institute drought and desertification combating measures are reviewed, highlighting the role that community action plays in reducing adverse effects in the region. Linkages to trade patterns that perpetuate poverty and unwise use of resources are discussed. Adopting ’people centred’ mitigating measures is emphasised. Success rests with both the people in the ’south’ and those in the ’north’. What is required is an informed global action.