Knowledge Resource Center for Ecological Environment in Arid Area
DOI | 10.3201/eid1006.030660 |
Environmental exposure and leptospirosis, Peru | |
Johnson, MAS; Smith, H; Joseph, P; Gilman, RH; Bautista, CT; Campos, KJ; Cespedes, M; Klatsky, P; Vidal, C; Terry, H; Calderon, MM; Coral, C; Cabrera, L; Parmar, PS; Vinetz, JM | |
通讯作者 | Vinetz, JM |
来源期刊 | EMERGING INFECTIOUS DISEASES
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ISSN | 1080-6040 |
EISSN | 1080-6059 |
出版年 | 2004 |
卷号 | 10期号:6页码:1016-1022 |
英文摘要 | Human infection by leptospires has highly variable clinical manifestations, which range from subclinical infection to fulminant disease. We conducted a population-based, cross-sectional seroepidemiologic study in Peru to determine potential relationships of environmental context to human exposure to Leptospira and disease associated with seroconversion. Three areas were studied: a flooded urban slum in the Peruvian Amazon city of Iquitos; rural: peri-Iquitos villages; and a desert shantytown near Lima. Seroprevalence in Belen was 28% (182/650); in rural areas, 17% (52/316); and in a desert shantytown, 0.7% (1/150). Leptospira-infected peridomestic rats were found in all locales. In Belen, 20 (12.4%) of 161 patients seroconverted between dry and wet seasons (an incidence rate of 288/1,000). Seroconversion was associated with history of febrile illness; severe leptospirosis was not seen. Human exposure to Leptospira in the Iquitos region is high, likely related both to the ubiquity of leptospires in the environment and human behavior conducive to transmission from infected zoonotic sources. |
类型 | Article |
语种 | 英语 |
国家 | USA ; Peru |
收录类别 | SCI-E |
WOS记录号 | WOS:000221749300007 |
WOS关键词 | RISK-FACTORS ; PULMONARY HEMORRHAGE ; INFECTION ; CHILDREN ; NICARAGUA ; OUTBREAK ; EPIDEMIC |
WOS类目 | Immunology ; Infectious Diseases |
WOS研究方向 | Immunology ; Infectious Diseases |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/146635 |
作者单位 | (1)Univ Calif San Diego, Sch Med, Div Infect Dis, Dept Med, La Jolla, CA 92093 USA;(2)Asoc Benef Prisma, Lima, Peru;(3)Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA;(4)USN Med Ctr Res Detachment, Lima, Peru;(5)Univ Peruana Caetano Heredia, Lima, Peru;(6)Minist Hlth, Iquitos, Peru |
推荐引用方式 GB/T 7714 | Johnson, MAS,Smith, H,Joseph, P,et al. Environmental exposure and leptospirosis, Peru[J],2004,10(6):1016-1022. |
APA | Johnson, MAS.,Smith, H.,Joseph, P.,Gilman, RH.,Bautista, CT.,...&Vinetz, JM.(2004).Environmental exposure and leptospirosis, Peru.EMERGING INFECTIOUS DISEASES,10(6),1016-1022. |
MLA | Johnson, MAS,et al."Environmental exposure and leptospirosis, Peru".EMERGING INFECTIOUS DISEASES 10.6(2004):1016-1022. |
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