干旱区生态环境知识资源中心(Arid): Isolation and structures of avicins D and G: In vitro tumor-inhibitory saponins derived from Acacia victoriae

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DOI	10.1021/np020400v
	Isolation and structures of avicins D and G: In vitro tumor-inhibitory saponins derived from Acacia victoriae
	Jayatilake, GS; Freeberg, DR; Liu, ZJ; Richheimer, SL; Blake, ME; Bailey, DT; Haridas, V; Gutterman, JU
通讯作者	Jayatilake, GS
来源期刊	JOURNAL OF NATURAL PRODUCTS
ISSN	0163-3864
EISSN	1520-6025
出版年	2003
卷号	66 期号:6 页码:779-783
英文摘要	Two new saponins named avicins D (1) and G (2) were isolated from the seed pods of the desert legume plant Acacia victoriae. The structures, elucidated by 1D and 2D NMR studies and by chemical means, were characterized as acacic acid-bearing oligosaccharides at C-3 and C-28 with a side chain linked to C-21 comprised of two monoterpene carboxylic acids and a quinovose moiety. Both compounds exhibited potent cytotoxicity (apoptosis) against human T-cell leukemia (Jurkat cells) in vitro.
类型	Article
语种	英语
国家	USA
收录类别	SCI-E
WOS记录号	WOS:000183814600009
WOS关键词	TRITERPENOID SAPONINS ; ALKALINE HYDROLYSATE ; ALBIZIA JULIBRISSIN ; CYTOTOXIC SAPONINS ; CONCINNA SAPONINS ; INDUCE APOPTOSIS ; GLYCOSIDES ; BENTHAM ; ASSIGNMENT ; FRACTION
WOS类目	Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy
WOS研究方向	Plant Sciences ; Pharmacology & Pharmacy
来源机构	Arizona State University
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/145278
作者单位	(1)Hauser Inc, Denver, CO 80221 USA;(2)Arizona State Univ, Dept Plant Biol, Tempe, AZ 85287 USA;(3)Univ Texas, MD Anderson Canc Ctr, Dept Mol Therapeut, Houston, TX 77030 USA
推荐引用方式 GB/T 7714	Jayatilake, GS,Freeberg, DR,Liu, ZJ,et al. Isolation and structures of avicins D and G: In vitro tumor-inhibitory saponins derived from Acacia victoriae[J]. Arizona State University,2003,66(6):779-783.
APA	Jayatilake, GS.,Freeberg, DR.,Liu, ZJ.,Richheimer, SL.,Blake, ME.,...&Gutterman, JU.(2003).Isolation and structures of avicins D and G: In vitro tumor-inhibitory saponins derived from Acacia victoriae.JOURNAL OF NATURAL PRODUCTS,66(6),779-783.
MLA	Jayatilake, GS,et al."Isolation and structures of avicins D and G: In vitro tumor-inhibitory saponins derived from Acacia victoriae".JOURNAL OF NATURAL PRODUCTS 66.6(2003):779-783.