Arid
DOI10.1016/S0041-0101(01)00254-9
Novel activities of saliva from the octopus Eledone cirrhosa (Mollusca; Cephalopoda)
Key, LN; Boyle, PR; Jaspars, M
通讯作者Key, LN
来源期刊TOXICON
ISSN0041-0101
出版年2002
卷号40期号:6页码:677-683
英文摘要

Haemolytic activity against mammalian erythrocytes was detected in very low concentrations of saliva from the octopus Eledone cirrhosa. It was not caused by any previously identified component of this saliva. The activity was slightly inhibited by trypsin and more drastically by chymotrypsin.


Locust bioassay was used to test HPLC fractions isolated from E. cirrhosa saliva. An LD50 of 378.4 ug/g locust weight was calculated for whole saliva injected into the desert locust Schistocerca gregaria.


This study was the first record of haemolytic activity and toxicity to insects in cephalopod saliva. Both haemolytic and insecticidal fractions could be separated using reversed phase HPLC. (C) 2002 Elsevier Science Ltd. All rights reserved.


英文关键词Eledone cirrhosa saliva haemolysis toxin
类型Article
语种英语
国家Scotland
收录类别SCI-E
WOS记录号WOS:000175810700003
WOS关键词VULGARIS
WOS类目Pharmacology & Pharmacy ; Toxicology
WOS研究方向Pharmacology & Pharmacy ; Toxicology
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/143849
作者单位(1)Univ Aberdeen, Dept Zool, Aberdeen AB24 2TZ, Scotland;(2)Univ Aberdeen, Dept Chem, Marine Nat Prod Lab, Old Aberdeen AB24 3UE, Scotland
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Key, LN,Boyle, PR,Jaspars, M. Novel activities of saliva from the octopus Eledone cirrhosa (Mollusca; Cephalopoda)[J],2002,40(6):677-683.
APA Key, LN,Boyle, PR,&Jaspars, M.(2002).Novel activities of saliva from the octopus Eledone cirrhosa (Mollusca; Cephalopoda).TOXICON,40(6),677-683.
MLA Key, LN,et al."Novel activities of saliva from the octopus Eledone cirrhosa (Mollusca; Cephalopoda)".TOXICON 40.6(2002):677-683.
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