干旱区生态环境知识资源中心(Arid): Study of on-line stacking procedures for analyzing marbofloxacin by capillary zone electrophoresis

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DOI	10.1007/BF02492905
	Study of on-line stacking procedures for analyzing marbofloxacin by capillary zone electrophoresis
	Hernandez, M; Borrull, F; Calull, M
通讯作者	Calull, M
来源期刊	CHROMATOGRAPHIA
ISSN	0009-5893
出版年	2002
卷号	55 期号:9-10 页码:585-590
英文摘要	This paper describes the analysis of marbofloxacin at low levels in pig plasma by capillary electrophoresis (CE). To increase the sensitivity of CE we studied two on-column stacking systems, field-amplified sample injection (FASI) and isotachophoresis (ITP), and optimized several conditions to obtain the best sensitivity with each. The best results were obtained by use of ITP-CZE with 10 mm sodium monohydrogen phosphate (pH 9.0) as the leading and background electrolytes and 10 mm beta-alanine (pH 9.0) as the terminating electrolyte. This system was 75 times more sensitive than conventional CE - the enhanced detection limit (LOD) was 20 mug kg(-1). A sample of pig plasma was analyzed after clean-up by solid-phase extraction on Oasis HLB cartridges and elution with methanol. Recoveries were approximately 100%.
英文关键词	capillary zone electrophoresis on-line stacking procedure marbofloxacin
类型	Article
语种	英语
国家	Spain
收录类别	SCI-E
WOS记录号	WOS:000176096100009
WOS关键词	PERFORMANCE LIQUID-CHROMATOGRAPHY ; FLUORESCENCE DETECTION ; QUINOLONES ; SEPARATION ; ISOTACHOPHORESIS ; SAMPLES ; PRECONCENTRATION ; OXYTETRACYCLINE ; IMPURITIES ; PREDICTION
WOS类目	Biochemical Research Methods ; Chemistry, Analytical
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/142321
作者单位	(1)Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43005, Spain
推荐引用方式 GB/T 7714	Hernandez, M,Borrull, F,Calull, M. Study of on-line stacking procedures for analyzing marbofloxacin by capillary zone electrophoresis[J],2002,55(9-10):585-590.
APA	Hernandez, M,Borrull, F,&Calull, M.(2002).Study of on-line stacking procedures for analyzing marbofloxacin by capillary zone electrophoresis.CHROMATOGRAPHIA,55(9-10),585-590.
MLA	Hernandez, M,et al."Study of on-line stacking procedures for analyzing marbofloxacin by capillary zone electrophoresis".CHROMATOGRAPHIA 55.9-10(2002):585-590.