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DOI | 10.1093/bja/87.3.421 |
Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anaesthetized with propofol or sevoflurane | |
Gugino, LA; Chabot, RJ; Prichep, LS; John, ER; Formanek, V; Aglio, LS | |
通讯作者 | Gugino, LA |
来源期刊 | BRITISH JOURNAL OF ANAESTHESIA
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ISSN | 0007-0912 |
EISSN | 1471-6771 |
出版年 | 2001 |
卷号 | 87期号:3页码:421-428 |
英文摘要 | Significant changes in topographic quantitative EEG (QEEG) features were documented during induction and emergence from anaesthesia induced by the systematic administration of sevoflurane and propofol in combination with remifentanil, The goal was to identify those changes that were sensitive to alterations in the state of consciousness but independent of anaesthetic protocol. Healthy paid volunteers were anaesthetized and reawakened using propofol/remifentanil and sevoflurane/remifentanil, administered in graded steps while the level of arousal was measured. Alterations in the level of arousal were accompanied by significant QEEG changes, many of which were consistent across anaesthetic protocols. Light sedation was accompanied by decreased posterior alpha and increased frontal/central beta power. Frontal power predominance increased with deeper sedation, involving alpha arid, to a lesser extent, delta and theta power. With loss of consciousness, delta and theta power increased further in anterior regions and also spread to posterior regions. These changes reversed with return to consciousness. |
英文关键词 | monitoring, quantitative EEG brain, neurometrics anaesthetics i.v., propofol anaesthetics volatile, sevoflurane anaesthesia, depth, conscious awareness |
类型 | Article |
语种 | 英语 |
国家 | USA |
收录类别 | SCI-E |
WOS记录号 | WOS:000171452400008 |
WOS关键词 | ELECTRICAL-ACTIVITY ; ELECTROENCEPHALOGRAPHY ; ANESTHESIA ; SEDATION ; BRAIN |
WOS类目 | Anesthesiology |
WOS研究方向 | Anesthesiology |
资源类型 | 期刊论文 |
条目标识符 | http://119.78.100.177/qdio/handle/2XILL650/140421 |
作者单位 | (1)Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Anesthesia, Boston, MA 02115 USA;(2)NYU, Sch Med, Dept Psychiat, Brain Res Labs, New York, NY USA;(3)NYS Dept Mental Hyg, Nathan S Kline Inst Psychiat Res, Orangeburg, NY USA |
推荐引用方式 GB/T 7714 | Gugino, LA,Chabot, RJ,Prichep, LS,et al. Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anaesthetized with propofol or sevoflurane[J],2001,87(3):421-428. |
APA | Gugino, LA,Chabot, RJ,Prichep, LS,John, ER,Formanek, V,&Aglio, LS.(2001).Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anaesthetized with propofol or sevoflurane.BRITISH JOURNAL OF ANAESTHESIA,87(3),421-428. |
MLA | Gugino, LA,et al."Quantitative EEG changes associated with loss and return of consciousness in healthy adult volunteers anaesthetized with propofol or sevoflurane".BRITISH JOURNAL OF ANAESTHESIA 87.3(2001):421-428. |
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