Arid
DOI10.1590/S0074-02762000000700021
Current millennium biotechniques for biomedical research on parasites and host-parasite interactions
Teixeira, ARL; Simoes-Barbosa, A; Faudry, E; Lozzi, SP; Arganaraz, ER; D’souza-Ault, M; Santana, JM
通讯作者Teixeira, ARL
来源期刊MEMORIAS DO INSTITUTO OSWALDO CRUZ
ISSN0074-0276
出版年2000
卷号95页码:123-131
英文摘要

The development of biotechnology in the last three decades has generated the feeling that the newest scientific achievements will deliver high standard quality of life through abundance of food and means for successfully combating diseases. Where the new biotechnologies give access to genetic information, there is a common belief that physiological and pathological processes result from subtle modifications of gene expression. Trustfully, modern genetics has produced genetic maps, physical maps and complete nucleotide sequences from 141 viruses, 51 organelles, two eubacteria, one archeon and one eukaryote (Saccharomices cerevisiae). In addition, during the Centennial Commemoration of the Oswaldo Cruz Institute the nearly complete human genome map was proudly announced: whereas the latest Brazilian key stone contribution to science was the publication of the Shillela fastidiosa genomic sequence highlythed on a Nature cover issue. There exists a belief among the populace that further scientific accomplishments will rapidly lead to new drugs and methodological approaches to cure genetic diseases and other incurable ailments. Yet, much evidence has been accumulated, showing that a large information gap exists between the knowledge of genome sequence arid our knowledge of genome function. Now that many genome maps are available, people wish to know what are we going to do with them. Certainly, all these scientific accomplishments will shed light on many move secrets of life. Nevertheless, parsimony in the weekly announcements of promising scientific achievements is necessary. We also need many move creative experimental biologists to discover Mew, as:vet tin-envisaged biotechnological approaches, and the basic resource needed for carrying out mile stone research necessary for leading us to that "promised land" often proclaimed by the mass media.


英文关键词genomics proteomics transcriptomics Chagas disease leishmaniasis post-genomics
类型Article ; Proceedings Paper
语种英语
国家Brazil
收录类别CPCI-S ; SCI-E
WOS记录号WOS:000165526400022
WOS关键词TRYPANOSOMA-CRUZI ; 2-DIMENSIONAL ELECTROPHORESIS ; DIFFERENTIAL DISPLAY ; GENE-EXPRESSION ; FUNCTIONAL GENOMICS ; SEQUENCE ; PROTEINS ; DISEASE ; MAP ; HYBRIDIZATION
WOS类目Parasitology ; Tropical Medicine
WOS研究方向Parasitology ; Tropical Medicine
资源类型期刊论文
条目标识符http://119.78.100.177/qdio/handle/2XILL650/139598
作者单位(1)Univ Brasilia, Fac Med, Lab Pesquisa Multidisciplinar Doenca Chagas, BR-70919970 Brasilia, DF, Brazil
推荐引用方式
GB/T 7714
Teixeira, ARL,Simoes-Barbosa, A,Faudry, E,et al. Current millennium biotechniques for biomedical research on parasites and host-parasite interactions[J],2000,95:123-131.
APA Teixeira, ARL.,Simoes-Barbosa, A.,Faudry, E.,Lozzi, SP.,Arganaraz, ER.,...&Santana, JM.(2000).Current millennium biotechniques for biomedical research on parasites and host-parasite interactions.MEMORIAS DO INSTITUTO OSWALDO CRUZ,95,123-131.
MLA Teixeira, ARL,et al."Current millennium biotechniques for biomedical research on parasites and host-parasite interactions".MEMORIAS DO INSTITUTO OSWALDO CRUZ 95(2000):123-131.
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