干旱区生态环境知识资源中心(Arid): Determination of oxytetracycline and some impurities in plasma by non-aqueous capillary electrophoresis using solid-phase extraction

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DOI	10.1007/BF02491017
	Determination of oxytetracycline and some impurities in plasma by non-aqueous capillary electrophoresis using solid-phase extraction
	Hernandez, M; Borrull, F; Calull, M
通讯作者	Hernandez, M
来源期刊	CHROMATOGRAPHIA
ISSN	0009-5893
出版年	2000
卷号	52 期号:5-6 页码:279-284
英文摘要	The potential of a non-aqueous, capillary electrophoresis (NACE) system for separating oxytetracycline from three of its impurities - tetracycline, 4-epioxytetracycline and 4-epitetracycline - using UV detection has been studied. The running buffer was: 25 mM sodium acetate, 1 mM EDTA. methanesulfonic acid, pH 4,dissolved in MeOH-ACN (50:50, v/v). The method was also used to determine these compounds in pig plasma. A solid-phase extraction (SPE) procedure as a clean-up step has also developed. For this we tested Sep Pak C-18, LiChrolut EN and OASIS cartridges. OASIS cartridges were best. Recoveries were 90 - 100% for all compounds except EOTC which had a recovery of 74%.
英文关键词	capillary zone electrophoresis non-aqueous medium solid-phase extraction tetracyclines plasma samples
类型	Article
语种	英语
国家	Spain
收录类别	SCI-E
WOS记录号	WOS:000089660600003
WOS关键词	PERFORMANCE LIQUID-CHROMATOGRAPHY ; TETRACYCLINE ANTIBIOTICS ; ANIMAL-TISSUES ; CHEMICAL-ANALYSIS ; NONAQUEOUS MEDIA ; RESIDUES ; SEPARATION ; IMPROVEMENT ; URINE ; MILK
WOS类目	Biochemical Research Methods ; Chemistry, Analytical
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/138757
作者单位	(1)Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43005, Spain
推荐引用方式 GB/T 7714	Hernandez, M,Borrull, F,Calull, M. Determination of oxytetracycline and some impurities in plasma by non-aqueous capillary electrophoresis using solid-phase extraction[J],2000,52(5-6):279-284.
APA	Hernandez, M,Borrull, F,&Calull, M.(2000).Determination of oxytetracycline and some impurities in plasma by non-aqueous capillary electrophoresis using solid-phase extraction.CHROMATOGRAPHIA,52(5-6),279-284.
MLA	Hernandez, M,et al."Determination of oxytetracycline and some impurities in plasma by non-aqueous capillary electrophoresis using solid-phase extraction".CHROMATOGRAPHIA 52.5-6(2000):279-284.