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Fourteen samples of white (WT), brown (BT), speckled (ST), and black (BKT) tepary beans (Phaseolus acutifolius) grown in the semiarid and arid areas of the southwestern U.S. and northern Mexico, were evaluated for their weight and sizes and analyzed for proximate composition, dietary fiber, trypsin inhibitor activity (TIA), and phytic acid (PA). Seed weight (0.105 g to 0.145 g) and size (7.1 x 5.0 mm to 9.3 x 6.4 mm) were not significantly different among WT, BT, ST and BKT. Protein (N x 6.25) and fat contents ranged from 17.3% to 23.1% and from 0.73% to 1.18%, respectively. No significant difference (P < 0.05) in protein and fat levels were observed among tepary types. Soluble, insoluble, and total dietary fiber were not significantly different. Total dietary fiber ranged from 17.97% to 20.96%. TIA (14.82 TIU to 24.58 TIU/mg sample) was not significantly different among raw tepary types. Autoclaving for 10 min and 20 min reduced significantly TIA. PA content (1.83 mg to 5.34 mg PA/g sample) was not significantly different among tepary types.