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The first U - Pb zircon ages are reported for the gneissic bedrock inliers previously interpreted as part of the Nile Craton. The inliers crop out in the Egyptian Western Desert, east of the Uweinat area and west of the Eastern Desert. Multi- and single-grain zircon analyses of granitoid gneiss and migmatite from Gebel Um Shagir, Aswan, and another locality approximately 160 km south-west of Aswan, yield simple discordia with near modern day Pb loss trajectories, and the following Neoproterozoic crystallization ages: 626 + 4/-3, 634 +/- 4 and 741 +/- 3 Ma. In contrast, multi- and single-grain U - Pb analyses (zircon and sphene) from an anorthositic gabbro at Gebel Kamil (22-degrees 46’N 26-degrees 21’E) and an anorthosite at Gebel El Asr (22-degrees 46’N 31-degrees 10’E) yield Archean and Paleoproterozoic emplacement ages. The former yield a crystallization age of > 2.67 Ga and a metamorphic age of almost-equal-to 2.0 Ga; the latter a metamorphic age of 0.69 Ga and an inheritance age of 1.9 - 2.1 Ga. Because high grade gneiss and migmatite of Neoproterozoic, Paleoproterozoic and Archean age crop out west of the Nile, pre-Neoproterozoic crust should no longer be identified by its metamorphic grade. By contrast, mapping the anorthosite and related rocks might provide first-order estimates for the extension of pre-Neoproterozoic crust in north-east Africa. It is suggested that Archean and Paleoproterozoic crust of the Uweinat and Congo Craton are contiguous because these U - Pb (zircon) data show no evidence for a Neoproterozoic thermal overprint in the Gebel Kamil area and there is no pronounced Neoproterozoic magmatic activity south of the Uweinat inlier and north of the Congo Craton.