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Seasonal changes in sugar and protein contents of some important halophytes in Indian desert have been studied and presented here. Plants at Jodhpur (site-II), which is non-saline, showed maximum sugar during summer season. Plant species at Pachpadra (site-I), which is extremely saline, indicated higher sugar during rains, when soil salinity is reduced. Crude protein declined under drought or saline stress at both sites. Plant species at site-II exhibited higher crude protein as compared to those at site-I.