干旱区生态环境知识资源中心(Arid): EFFECTS OF THE ADENYLATE-CYCLASE ACTIVATOR FORSKOLIN AND ITS INACTIVE DERIVATIVE 1,9-DIDEOXYFORSKOLIN ON INSECT CYTOCHROME-P-450 DEPENDENT STEROID HYDROXYLASE-ACTIVITY

Arid

DOI	10.1007/BF01923603
	EFFECTS OF THE ADENYLATE-CYCLASE ACTIVATOR FORSKOLIN AND ITS INACTIVE DERIVATIVE 1,9-DIDEOXYFORSKOLIN ON INSECT CYTOCHROME-P-450 DEPENDENT STEROID HYDROXYLASE-ACTIVITY
	KEOGH, DP; MITCHELL, MJ; CROOKS, JR; SMITH, SL
来源期刊	EXPERIENTIA
ISSN	0014-4754
出版年	1992
卷号	48 期号:1 页码:39-41
英文摘要	The adenylate cyclase activator forskolin and its pharmacologically inactive derivative 1,9-dideoxyforskolin were found to inhibit in a dose-dependent fashion the ecdysone 20-monooxygenase activity associated with wandering stage larvae of Drosophila melanogaster and fat body and midgut from last instar larvae of the tobacco hornworm, Manduca sexta. The concentrations of these labdane diterpenes required to elicit a 50% inhibition of the cytochrome P-450 dependent steroid hydroxylase activity in the insect tissues ranged from approximately 5 x 10(-6) to 5 x 10(-4) M.
英文关键词	ADENYLATE CYCLASE CYTOCHROME P-450 ECDYSONE 20-MONOOXYGENASE FORSKOLIN STEROID HYDROXYLASE
类型	Article
语种	英语
国家	USA
收录类别	SCI-E
WOS记录号	WOS:A1992HC94200012
WOS关键词	ECDYSONE 20-MONOOXYGENASE ACTIVITY ; LARVAL-PUPAL DEVELOPMENT ; MANDUCA-SEXTA ; CYCLIC-AMP ; ALPHA-ECDYSONE ; DROSOPHILA-MELANOGASTER ; SCHISTOCERCA-GREGARIA ; REVERSIBLE ACTIVATION ; LOCUSTA-MIGRATORIA ; DESERT LOCUST
WOS类目	Multidisciplinary Sciences
WOS研究方向	Science & Technology - Other Topics
资源类型	期刊论文
条目标识符	http://119.78.100.177/qdio/handle/2XILL650/127582
作者单位	(1)BOWLING GREEN STATE UNIV,DEPT BIOL SCI,BOWLING GREEN,OH 43403
推荐引用方式 GB/T 7714	KEOGH, DP,MITCHELL, MJ,CROOKS, JR,et al. EFFECTS OF THE ADENYLATE-CYCLASE ACTIVATOR FORSKOLIN AND ITS INACTIVE DERIVATIVE 1,9-DIDEOXYFORSKOLIN ON INSECT CYTOCHROME-P-450 DEPENDENT STEROID HYDROXYLASE-ACTIVITY[J],1992,48(1):39-41.
APA	KEOGH, DP,MITCHELL, MJ,CROOKS, JR,&SMITH, SL.(1992).EFFECTS OF THE ADENYLATE-CYCLASE ACTIVATOR FORSKOLIN AND ITS INACTIVE DERIVATIVE 1,9-DIDEOXYFORSKOLIN ON INSECT CYTOCHROME-P-450 DEPENDENT STEROID HYDROXYLASE-ACTIVITY.EXPERIENTIA,48(1),39-41.
MLA	KEOGH, DP,et al."EFFECTS OF THE ADENYLATE-CYCLASE ACTIVATOR FORSKOLIN AND ITS INACTIVE DERIVATIVE 1,9-DIDEOXYFORSKOLIN ON INSECT CYTOCHROME-P-450 DEPENDENT STEROID HYDROXYLASE-ACTIVITY".EXPERIENTIA 48.1(1992):39-41.